痛觉过敏、异常性疼痛和最终过量：慢性阿片类药物使用的问题。

Q3 Medicine

Journal of opioid management Pub Date : 2025-07-01 DOI:10.5055/jom.0891

Steven Sochacki

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引用次数: 0

摘要

众所周知，阿片类药物会带来一些相对温和的副作用，这还不包括它们的成瘾性。这篇综述将着眼于患者，特别是慢性疼痛患者长期服用阿片类药物时发生的一些副作用。这些副作用包括阿片类药物引起的痛觉过敏和异常性疼痛。过量和因素，包括痛觉过敏和异常性疼痛，使患者更有可能过量，是另一个主题将涉及。关于阿片类药物引起的痛觉过敏或异常性疼痛的治疗，人类受试者的研究并不多，但其中一些研究也将在本综述中进行简要探讨。

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Hyperalgesia, allodynia, and eventual overdose: The problems with chronic opioid use.

Opioids are known to come with some relatively benign side effects, not including their addictive potential. This review will look at some of the side effects that occur when patients, especially chronic pain patients, take opioids chronically. These side effects include both hyperalgesia and allodynia caused by opioids. Overdose and factors, including hyperalgesia and allodynia, that make a patient more likely to overdose, is the other topic that will be covered. Not much research has been done with human subjects regarding treatment of opioid induced hyperalgesia or allodynia, but some of this research will also be briefly explored throughout this review.

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来源期刊

Journal of opioid management Medicine-Anesthesiology and Pain Medicine

CiteScore

1.00

自引率

0.00%

发文量

期刊介绍： The Journal of Opioid Management deals with all aspects of opioids. From basic science, pre-clinical, clinical, abuse, compliance and addiction medicine, the journal provides and unbiased forum for researchers and clinicians to explore and manage the complexities of opioid prescription.