miR - 141在人卵巢癌细胞系和组织中抑制SIK1的研究

IF 5.8 3区 医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL
International journal of molecular medicine Pub Date : 2025-11-01 Epub Date: 2025-09-05 DOI:10.3892/ijmm.2025.5627
Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
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引用次数: 0

摘要

在这篇论文发表之后,对于图1A所示的western blots,在卵巢癌组织中检测到盐诱导激酶1的表达水平,一位关心的读者引起了编辑的注意,患者4、6和7的β -肌动蛋白负载对照在外观上惊人地相似。此外,该图中的几个蛋白质条带与随后发表在《实验与治疗医学》杂志上的另一篇由不同研究机构的不同作者撰写的论文中的数据惊人地相似,尽管这篇论文已被撤回。编辑部联系了作者,要求他们解释这篇论文中数据呈现的明显异常,尽管到目前为止,作者还没有任何回应。由于编辑部已经意识到围绕本文科学完整性的潜在问题,在编辑部继续进一步调查此事的同时,我们发出一份关注表达,通知读者这一潜在问题。[j]国际分子医学杂志37:1601 - 1610,2016;DOI: 10.3892 / ijmm.2016.2553]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Expression of Concern] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues.

Following the publication of this paper, for the western blots shown in Fig. 1A, where the expression levels of salt‑inducible kinase 1 were detected in ovarian cancer tissues, it was drawn to the Editor's attention by a concerned reader that the β‑actin loading controls for patients 4, 6 and 7 were strikingly similar in appearance. Moreover, several of the protein bands in this figure were strikingly similar to data which subsequently appeared in another paper written by different authors at different research institutes that was published in the journal Experimental and Therapeutic Medicine, although this paper has since been retracted. The authors were contacted by the Editorial Office to offer an explanation for this apparent anomaly in the presentation of the data in this paper, although up to this time, no response from the authors has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [International Journal of Molecular Medicine 37: 1601‑1610, 2016; DOI: 10.3892/ijmm.2016.2553].

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来源期刊
International journal of molecular medicine
International journal of molecular medicine 医学-医学:研究与实验
CiteScore
12.30
自引率
0.00%
发文量
124
审稿时长
3 months
期刊介绍: The main aim of Spandidos Publications is to facilitate scientific communication in a clear, concise and objective manner, while striving to provide prompt publication of original works of high quality. The journals largely concentrate on molecular and experimental medicine, oncology, clinical and experimental cancer treatment and biomedical research. All journals published by Spandidos Publications Ltd. maintain the highest standards of quality, and the members of their Editorial Boards are world-renowned scientists.
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