多巴胺作为一种教学信号：理解它在塑造个体行为中的作用

IF 52.7 1区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Signal Transduction and Targeted Therapy Pub Date : 2025-09-05 DOI:10.1038/s41392-025-02406-5

Seung Chan Kim, Sehwan Kim, Sang Ryong Kim

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引用次数: 0

摘要

在最近发表在《细胞》杂志上的一篇文章中，Liebana和他的同事们证明了多巴胺作为一种电路特定的教学信号，随着时间的推移塑造了个体的学习轨迹。这些奖励预测误差（RPE）信号通过选择性地强化神经通路来改善行为，揭示了多巴胺引导个性化学习策略超越经典奖励模型的关键机制

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Dopamine as a teaching signal: understanding its role in shaping individual behavior

查看原文本刊更多论文

Dopamine as a teaching signal: understanding its role in shaping individual behavior

In a recent publication in Cell, Liebana and colleagues demonstrate that dopamine acts as a circuit-specific teaching signal, shaping individual learning trajectories over time. These reward prediction error (RPE) signals refine behavior by selectively reinforcing neural pathways, revealing a key mechanism through which dopamine guides personalized learning strategies beyond classical reward-based models.¹

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来源期刊

Signal Transduction and Targeted Therapy Biochemistry, Genetics and Molecular Biology-Genetics

CiteScore

44.50

自引率

1.50%

发文量

384

审稿时长

5 weeks

期刊介绍： Signal Transduction and Targeted Therapy is an open access journal that focuses on timely publication of cutting-edge discoveries and advancements in basic science and clinical research related to signal transduction and targeted therapy. Scope: The journal covers research on major human diseases, including, but not limited to: Cancer,Cardiovascular diseases,Autoimmune diseases,Nervous system diseases.