影像学洞察儿童肝脏肿块:肝病学实践的综合回顾。

IF 2.5 Q2 GASTROENTEROLOGY & HEPATOLOGY
Mina'a Shahid, Kiran Hilal, Memoona Khan, Zainab Haider Ejaz, Sadaf Altaf, Saleem Islam, Kumail Khandwala
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引用次数: 0

摘要

儿童肝脏肿块包括多种良性和恶性病变,根据患者年龄有不同的模式。最佳影像对及时诊断、管理和预后至关重要。本文将小儿肝脏肿块按年龄组进行分类,以指导肝病学和放射学实践,并强调影像学特征。在出生至6岁的儿童中,最常见的肝脏肿块包括肝母细胞瘤,这是该年龄组中最常见的原发性肝脏恶性肿瘤;婴儿血管瘤,一种具有特征性影像学表现的良性血管肿瘤;还有间充质错构瘤,一种罕见的发育性病变。对于大于6岁的儿童,肝脏肿块明显,以肝细胞癌为主要的恶性病变。良性肿块如局灶性结节增生和肝细胞腺瘤也出现在这个年龄段,通常与激素影响或代谢紊乱有关。在所有儿童年龄组中观察到的肿块包括肝囊肿、胆管囊肿、包虫病囊肿、化脓性和阿米巴脓肿、结核、淋巴瘤和转移性脓肿,每一种肿块都有独特的影像学特征,对鉴别诊断至关重要。这篇小型综述提供了一个全面的、基于年龄的儿科肝脏肿块的概述,重点关注临床表现和关键影像学发现,以支持临床肝病学的准确诊断和优化管理策略,特别是在资源匮乏的情况下。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Imaging insights into pediatric liver masses: A comprehensive minireview for hepatology practice.

Pediatric liver masses encompass a diverse spectrum of benign and malignant lesions, with distinct patterns based on patient age. Optimal imaging is critical for timely diagnosis, management, and prognosis. This pictorial minireview categorizes pediatric liver masses by age group to guide hepatology and radiology practice, with an emphasis on imaging characteristics. In children from birth to six years of age, the most common liver masses include hepatoblastoma, the most common primary hepatic malignancy in this age group; infantile hemangioma, a benign vascular tumor with a characteristic appearance on imaging; and mesenchymal hamartoma, a rare developmental lesion. For children older than six years, liver masses are distinct, with hepatocellular carcinoma being the predominant malignant lesion. Benign masses such as focal nodular hyperplasia and hepatocellular adenoma also emerge in this age range, often linked to hormonal influences or metabolic disorders. The masses observed across all pediatric age groups include hepatic cysts, choledochal cysts, hydatid cysts, pyogenic and amebic abscesses, tuberculosis, lymphoma, and metastases, each presenting with unique imaging features essential for differential diagnosis. This minireview provides a comprehensive, age-based overview of pediatric liver masses, focusing on clinical presentation and key imaging findings to support accurate diagnosis and optimize management strategies in clinical hepatology, particularly in low resource settings.

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来源期刊
World Journal of Hepatology
World Journal of Hepatology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
4.10
自引率
4.20%
发文量
172
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