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引用次数: 0
摘要
脊髓机械损伤可引起神经和分子病理生理反应。生物标志物正在成为一种有前途的公正的工具，可以评估脊髓损伤（SCI）后的病理生理过程。在这篇简明的综述中，我们提供了结构，包括神经丝蛋白（NF），胶质纤维酸性蛋白（GFAP）， Cleaved Tau (C-Tau), S100-β，神经元特异性烯醇酶（NSE），髓鞘碱性蛋白（MBP）和炎症，包括转化生长因子β (TGF-β)，肿瘤坏死因子（TNF），白细胞介素（il），可溶性CD95配体（sCD95L）生物标志物在报道的人类和动物SCI研究中的作用和表达的细节。
Promising Biomarkers for Spinal Cord Injury: A Brief Review.
Mechanical trauma to the spinal cord leads to neural and molecular pathophysiological responses. Biomarkers are emerging as a promising unbiased tool that can assess the pathophysiological processes following spinal cord injury (SCI). In this concise review, we provide details of role and expression of structural, including Neurofilament Proteins (NF), Glial Fibrillary Acidic Protein (GFAP), Cleaved Tau (C-Tau), S100-β, Neuron Specific Enolase (NSE), Myelin Basic Protein (MBP), and inflammatory, including Transforming Growth Factor Beta (TGF-β), Tumor Necrosis Factor (TNF), Interleukins (ILs), Soluble CD95 Ligand (sCD95L) biomarkers in reported human and animal SCI studies.
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