{"title":"从收益到肝脏疼痛：当运动训练过度时。","authors":"Benjamin I Burke, John J McCarthy, Ahmed Ismaeel","doi":"10.20517/evcna.2025.36","DOIUrl":null,"url":null,"abstract":"<p><p>A recent study from Liu <i>et al.</i> described the role of skeletal muscle-derived extracellular vesicles in promoting liver fibrosis as an outcome of chronic overtraining in mice. Here, we highlight this work and discuss its implications within the fields of exercise physiology and inter-organ communication.</p>","PeriodicalId":520322,"journal":{"name":"Extracellular vesicles and circulating nucleic acids","volume":"6 2","pages":"324-327"},"PeriodicalIF":4.8000,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12367453/pdf/","citationCount":"0","resultStr":"{\"title\":\"From gains to liver pain: when exercise training goes too far.\",\"authors\":\"Benjamin I Burke, John J McCarthy, Ahmed Ismaeel\",\"doi\":\"10.20517/evcna.2025.36\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A recent study from Liu <i>et al.</i> described the role of skeletal muscle-derived extracellular vesicles in promoting liver fibrosis as an outcome of chronic overtraining in mice. Here, we highlight this work and discuss its implications within the fields of exercise physiology and inter-organ communication.</p>\",\"PeriodicalId\":520322,\"journal\":{\"name\":\"Extracellular vesicles and circulating nucleic acids\",\"volume\":\"6 2\",\"pages\":\"324-327\"},\"PeriodicalIF\":4.8000,\"publicationDate\":\"2025-06-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12367453/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Extracellular vesicles and circulating nucleic acids\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.20517/evcna.2025.36\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Extracellular vesicles and circulating nucleic acids","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20517/evcna.2025.36","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
From gains to liver pain: when exercise training goes too far.
A recent study from Liu et al. described the role of skeletal muscle-derived extracellular vesicles in promoting liver fibrosis as an outcome of chronic overtraining in mice. Here, we highlight this work and discuss its implications within the fields of exercise physiology and inter-organ communication.
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