经椎间孔硬膜外类固醇注射与大容量腰椎竖立者脊柱阻滞治疗腰痛和神经根痛的随机临床试验

Rigved Arsh Singhrol, Dr Reena, Amrita Rath, Anil Kumar Paswan, Shashi Prakash, Nimisha Verma, Ashutosh Vikram
{"title":"经椎间孔硬膜外类固醇注射与大容量腰椎竖立者脊柱阻滞治疗腰痛和神经根痛的随机临床试验","authors":"Rigved Arsh Singhrol, Dr Reena, Amrita Rath, Anil Kumar Paswan, Shashi Prakash, Nimisha Verma, Ashutosh Vikram","doi":"10.14744/agri.2024.57983","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Transforaminal lumbar epidural steroid injection (TFESI) has been used to treat lumbar radiculopathies. Erector spinae plane block (ESPB) has been employed to provide postoperative analgesia following spine and back surgeries. We aimed to compare TFESI with high-volume lumbar ESPB in patients with low backache and radicular pain.</p><p><strong>Methods: </strong>This was a prospective, randomized, single-centre interventional study. After obtaining institutional ethical committee clearance and written informed consent, 60 patients aged 18 to 50 years with unilateral low backache were randomly allocated into two groups of 30 each-Group T and Group E. Group E received ultrasound-guided lumbar ESPB with 30 mL of 0.25% bupivacaine and 20 mg triamcinolone, whereas Group T received fluoroscopy-guided TFESI with 2 mL of 0.25% bupivacaine and 20 mg triamcinolone. The primary outcome was pain relief as assessed by the numeric rating scale (NRS) at 3 months. Secondary outcomes included NRS at 1 hour and 1 month, the Modified Oswestry Disability Index (MODI), the number of patients requiring rescue analgesia, and procedure-related complications.</p><p><strong>Results: </strong>The mean post-procedure NRS scores at 1 hour, 1 month, and 3 months were significantly lower in Group T compared to Group E (p=0.001, 0.013, and 0.007, respectively). MODI scores were significantly lower in both groups after treatment (p<0.001). In Group T, 6.9% of patients experienced a vasovagal attack and 3.4% had flushing, both of which resolved spontaneously. In contrast, no complications were observed in Group E.</p><p><strong>Conclusion: </strong>ESPB is effective for providing analgesia in patients with chronic low back pain and radiculopathy; however, TFESI showed superior pain relief as reflected in more favourable NRS scores. Nevertheless, TFESI requires greater precision and expertise and carries a higher risk of serious complications. ESPB may be a safer alternative when TFESI is difficult to perform or contraindicated.</p>","PeriodicalId":101341,"journal":{"name":"Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology","volume":"37 3","pages":"142-148"},"PeriodicalIF":0.0000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Transforaminal epidural steroid injection versus high-volume lumbar erector spinae block in patients with low backache and radicular pain - a randomized clinical trial.\",\"authors\":\"Rigved Arsh Singhrol, Dr Reena, Amrita Rath, Anil Kumar Paswan, Shashi Prakash, Nimisha Verma, Ashutosh Vikram\",\"doi\":\"10.14744/agri.2024.57983\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>Transforaminal lumbar epidural steroid injection (TFESI) has been used to treat lumbar radiculopathies. Erector spinae plane block (ESPB) has been employed to provide postoperative analgesia following spine and back surgeries. We aimed to compare TFESI with high-volume lumbar ESPB in patients with low backache and radicular pain.</p><p><strong>Methods: </strong>This was a prospective, randomized, single-centre interventional study. After obtaining institutional ethical committee clearance and written informed consent, 60 patients aged 18 to 50 years with unilateral low backache were randomly allocated into two groups of 30 each-Group T and Group E. Group E received ultrasound-guided lumbar ESPB with 30 mL of 0.25% bupivacaine and 20 mg triamcinolone, whereas Group T received fluoroscopy-guided TFESI with 2 mL of 0.25% bupivacaine and 20 mg triamcinolone. The primary outcome was pain relief as assessed by the numeric rating scale (NRS) at 3 months. Secondary outcomes included NRS at 1 hour and 1 month, the Modified Oswestry Disability Index (MODI), the number of patients requiring rescue analgesia, and procedure-related complications.</p><p><strong>Results: </strong>The mean post-procedure NRS scores at 1 hour, 1 month, and 3 months were significantly lower in Group T compared to Group E (p=0.001, 0.013, and 0.007, respectively). MODI scores were significantly lower in both groups after treatment (p<0.001). In Group T, 6.9% of patients experienced a vasovagal attack and 3.4% had flushing, both of which resolved spontaneously. In contrast, no complications were observed in Group E.</p><p><strong>Conclusion: </strong>ESPB is effective for providing analgesia in patients with chronic low back pain and radiculopathy; however, TFESI showed superior pain relief as reflected in more favourable NRS scores. Nevertheless, TFESI requires greater precision and expertise and carries a higher risk of serious complications. ESPB may be a safer alternative when TFESI is difficult to perform or contraindicated.</p>\",\"PeriodicalId\":101341,\"journal\":{\"name\":\"Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology\",\"volume\":\"37 3\",\"pages\":\"142-148\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.14744/agri.2024.57983\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14744/agri.2024.57983","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

目的:经椎间孔腰椎硬膜外类固醇注射(TFESI)已被用于治疗腰椎神经根病。直立脊柱平面阻滞(ESPB)已被用于脊柱和背部手术后的术后镇痛。我们的目的是比较TFESI和大容量腰椎ESPB对腰痛和神经根痛患者的治疗效果。方法:这是一项前瞻性、随机、单中心介入研究。在获得机构伦理委员会批准和书面知情同意后,将60例18 ~ 50岁单侧腰痛患者随机分为T组和E组,每组30例。E组接受超声引导下腰ESPB, 0.25%布比卡因30 mL,曲安奈德20 mg。T组接受透视引导下TFESI, 0.25%布比卡因2 mL,曲安奈德20 mg。主要结局是3个月时通过数字评定量表(NRS)评估疼痛缓解。次要结局包括1小时和1个月时的NRS、改良Oswestry残疾指数(Modified Oswestry Disability Index, MODI)、需要抢救性镇痛的患者数量和手术相关并发症。结果:T组术后1小时、1个月和3个月的平均NRS评分明显低于E组(p分别为0.001、0.013和0.007)。治疗后两组患者的MODI评分均显著降低(p结论:ESPB对慢性腰痛和神经根病患者镇痛有效;然而,TFESI在更有利的NRS评分中显示出更优越的疼痛缓解效果。然而,TFESI需要更高的精确度和专业知识,并且有更高的严重并发症风险。当TFESI难以实施或有禁忌时,ESPB可能是一种更安全的选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Transforaminal epidural steroid injection versus high-volume lumbar erector spinae block in patients with low backache and radicular pain - a randomized clinical trial.

Objectives: Transforaminal lumbar epidural steroid injection (TFESI) has been used to treat lumbar radiculopathies. Erector spinae plane block (ESPB) has been employed to provide postoperative analgesia following spine and back surgeries. We aimed to compare TFESI with high-volume lumbar ESPB in patients with low backache and radicular pain.

Methods: This was a prospective, randomized, single-centre interventional study. After obtaining institutional ethical committee clearance and written informed consent, 60 patients aged 18 to 50 years with unilateral low backache were randomly allocated into two groups of 30 each-Group T and Group E. Group E received ultrasound-guided lumbar ESPB with 30 mL of 0.25% bupivacaine and 20 mg triamcinolone, whereas Group T received fluoroscopy-guided TFESI with 2 mL of 0.25% bupivacaine and 20 mg triamcinolone. The primary outcome was pain relief as assessed by the numeric rating scale (NRS) at 3 months. Secondary outcomes included NRS at 1 hour and 1 month, the Modified Oswestry Disability Index (MODI), the number of patients requiring rescue analgesia, and procedure-related complications.

Results: The mean post-procedure NRS scores at 1 hour, 1 month, and 3 months were significantly lower in Group T compared to Group E (p=0.001, 0.013, and 0.007, respectively). MODI scores were significantly lower in both groups after treatment (p<0.001). In Group T, 6.9% of patients experienced a vasovagal attack and 3.4% had flushing, both of which resolved spontaneously. In contrast, no complications were observed in Group E.

Conclusion: ESPB is effective for providing analgesia in patients with chronic low back pain and radiculopathy; however, TFESI showed superior pain relief as reflected in more favourable NRS scores. Nevertheless, TFESI requires greater precision and expertise and carries a higher risk of serious complications. ESPB may be a safer alternative when TFESI is difficult to perform or contraindicated.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信