预测慢性阻塞性肺疾病患者药物依从性的因素:来自横断面研究的证据

Journal of caring sciences Pub Date : 2025-06-03 eCollection Date: 2025-07-01 DOI:10.34172/jcs.025.33204
Le Huyen Trinh, Luu Thi Thuy, Nguyen Thi Bich Hop, Tran Thi Hoang Oanh, Pham Thi Thuy
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引用次数: 0

摘要

药物依从性对于慢性阻塞性肺疾病(COPD)的有效治疗至关重要。然而,由于各种因素的影响,COPD患者的药物依从率普遍较低。本研究旨在确定越南COPD患者药物依从性的预测因素。方法:在越南中部一家三级医院进行横断面研究。在2022年3月至6月期间,共招募了104名诊断为COPD的患者。数据采用三份结构化问卷收集,包括人口统计学和健康相关特征表、药物信念问卷和一般药物依从性量表(GMAS)。数据分析采用描述性统计、独立t检验、卡方检验、单因素logistic回归分析和多因素logistic回归分析。结果:高达41.3%的参与者坚持服药。服药依从性在年轻人、受教育程度在高中以上的人、服药较少的人以及对服药必要性持更积极信念的人中较高。结论:整体依从率为中等。年龄、受教育程度、用药次数和对用药必要性的认识对其有显著影响。这些发现表明,医疗保健提供者应优先识别和支持有不依从性风险的患者。此外,干预方案应旨在提高患者对药物治疗COPD必要性的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Factors Predicting Medication Adherence in Patients with Chronic Obstructive Pulmonary Disease: Evidence from a Cross-Sectional Study.

Introduction: Medication adherence is crucial for effective management of chronic obstructive pulmonary disease (COPD). However, the medication adherence rates among patients with COPD is generally low due to various influencing factors. This study aimed to identify predictors of medication adherence among Vietnamese patients with COPD.

Methods: A cross-sectional study was conducted at a tertiary hospital in Central Vietnam. A total of 104 patients diagnosed with COPD were conveniently recruited between March and June 2022. Data were collected using three structured questionnaires, including demographic and health-related characteristics form, the Beliefs about Medicines Questionnaire, and the General Medication Adherence Scale (GMAS). Descriptive statistics, independent t-test, Chi-square test, univariate logistic regression analysis, and multivariable logistic regression were used for data analysis.

Results: Up to 41.3% of participants adhered to medication. Medication adherence was higher among younger individuals, those with education levels above high school, those with fewer medications, and those who held a stronger positive belief about the necessity of medication.

Conclusion: The overall medication adherence rate was moderate. It was significantly influenced by age, educational level, number of medications, and beliefs about the necessity of medication. These findings suggest that healthcare providers should prioritize identifying and supporting patients who are at risk of non-adherence. Moreover, intervention programs should aim to enhance patients' awareness of the necessity of medication in managing COPD.

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