Félix Del Campo, Tania M Álvaro de Castro, Raúl López-Izquierdo, Fernando Moreno Torrero, Daniel Álvarez, Gonzalo C Gutiérrez-Tobal, Roberto Hornero, Tomás Ruiz Albi
{"title":"颗粒物与慢性阻塞性肺疾病的恶化:低污染地区急诊科就诊分析","authors":"Félix Del Campo, Tania M Álvaro de Castro, Raúl López-Izquierdo, Fernando Moreno Torrero, Daniel Álvarez, Gonzalo C Gutiérrez-Tobal, Roberto Hornero, Tomás Ruiz Albi","doi":"10.55633/s3me/052.2025","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the association between particulate matter concentration (PM10 and PM2.5) and the number of emergency department visits for exacerbation of chronic obstructive pulmonary disease (COPD) in a low-pollution area.</p><p><strong>Methods: </strong>We conducted an ecological study based on emergency department visits for COPD exacerbations. A generalized additive model was used to estimate the relative risk and attributable fraction (AF), adjusting for weather variables. Pollution levels on the day of the visit and the 5 preceding days were considered to assess potential delayed effects of exposure.</p><p><strong>Results: </strong>A total of 2,045 patients with 5,233 emergency department visits were included. A total of 79.1% of the patients were men. The mean age was 79.5 years (SD, 10.1). The mean concentration of PM2.5 and PM10 was 11.5 µg/m³ and 17.3 µg/m³, respectively. Both emergency visits and particulate matter concentrations showed a seasonalpattern. A significant association was found with exposure occurring 3 days prior (lag -3), with a 5.8% increase in visits for every 10 µg/m³ increase in PM2.5 (AF 5.45%) and a 3.3% increase for PM10 (AF 3.15%). Men and patients older than 75 years showed greater sensitivity to exposure. The impact of particulate matter was more pronounced during the summer months.</p><p><strong>Conclusions: </strong>Exposure to PM2.5 and PM10 is associated with an increase in emergency department visits for COPD exacerbations, with a particular impact among men, patients older than 75 years, and during the summer season.</p>","PeriodicalId":93987,"journal":{"name":"Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias","volume":"37 4","pages":"267-273"},"PeriodicalIF":6.3000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Particulate matter and exacerbations of chronic obstructive pulmonary disease: analysis of emergency department visits in a low-pollution area.\",\"authors\":\"Félix Del Campo, Tania M Álvaro de Castro, Raúl López-Izquierdo, Fernando Moreno Torrero, Daniel Álvarez, Gonzalo C Gutiérrez-Tobal, Roberto Hornero, Tomás Ruiz Albi\",\"doi\":\"10.55633/s3me/052.2025\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To evaluate the association between particulate matter concentration (PM10 and PM2.5) and the number of emergency department visits for exacerbation of chronic obstructive pulmonary disease (COPD) in a low-pollution area.</p><p><strong>Methods: </strong>We conducted an ecological study based on emergency department visits for COPD exacerbations. A generalized additive model was used to estimate the relative risk and attributable fraction (AF), adjusting for weather variables. Pollution levels on the day of the visit and the 5 preceding days were considered to assess potential delayed effects of exposure.</p><p><strong>Results: </strong>A total of 2,045 patients with 5,233 emergency department visits were included. A total of 79.1% of the patients were men. The mean age was 79.5 years (SD, 10.1). The mean concentration of PM2.5 and PM10 was 11.5 µg/m³ and 17.3 µg/m³, respectively. Both emergency visits and particulate matter concentrations showed a seasonalpattern. A significant association was found with exposure occurring 3 days prior (lag -3), with a 5.8% increase in visits for every 10 µg/m³ increase in PM2.5 (AF 5.45%) and a 3.3% increase for PM10 (AF 3.15%). Men and patients older than 75 years showed greater sensitivity to exposure. The impact of particulate matter was more pronounced during the summer months.</p><p><strong>Conclusions: </strong>Exposure to PM2.5 and PM10 is associated with an increase in emergency department visits for COPD exacerbations, with a particular impact among men, patients older than 75 years, and during the summer season.</p>\",\"PeriodicalId\":93987,\"journal\":{\"name\":\"Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias\",\"volume\":\"37 4\",\"pages\":\"267-273\"},\"PeriodicalIF\":6.3000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.55633/s3me/052.2025\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.55633/s3me/052.2025","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Particulate matter and exacerbations of chronic obstructive pulmonary disease: analysis of emergency department visits in a low-pollution area.
Objective: To evaluate the association between particulate matter concentration (PM10 and PM2.5) and the number of emergency department visits for exacerbation of chronic obstructive pulmonary disease (COPD) in a low-pollution area.
Methods: We conducted an ecological study based on emergency department visits for COPD exacerbations. A generalized additive model was used to estimate the relative risk and attributable fraction (AF), adjusting for weather variables. Pollution levels on the day of the visit and the 5 preceding days were considered to assess potential delayed effects of exposure.
Results: A total of 2,045 patients with 5,233 emergency department visits were included. A total of 79.1% of the patients were men. The mean age was 79.5 years (SD, 10.1). The mean concentration of PM2.5 and PM10 was 11.5 µg/m³ and 17.3 µg/m³, respectively. Both emergency visits and particulate matter concentrations showed a seasonalpattern. A significant association was found with exposure occurring 3 days prior (lag -3), with a 5.8% increase in visits for every 10 µg/m³ increase in PM2.5 (AF 5.45%) and a 3.3% increase for PM10 (AF 3.15%). Men and patients older than 75 years showed greater sensitivity to exposure. The impact of particulate matter was more pronounced during the summer months.
Conclusions: Exposure to PM2.5 and PM10 is associated with an increase in emergency department visits for COPD exacerbations, with a particular impact among men, patients older than 75 years, and during the summer season.