美国成年人心力衰竭和心力衰竭合并肥胖死亡率的趋势和差异:1999-2020年CDC WONDER数据对地理、性别和种族差异的分析

IF 3
Journal of multimorbidity and comorbidity Pub Date : 2025-08-27 eCollection Date: 2025-01-01 DOI:10.1177/26335565251370816
Faizan Ahmed, Tehmasp Rehman Mirza, Sherif Eltawansy, Zaima Afzaal, Areeba Ahsan, Hira Zahid, Kainat Aman, Mushood Ahmed, Hritvik Jain, Muhammad Abdullah Naveed, Omar Kamel, Aman Ullah, Nisar Asmi, Farman Ali, Adnan Bhat, Paweł Łajczak, Ogechukwu Obi, Naveen Baskaran, Mian Zahid Khan Kakakhel, Ayesha Samad, Haitham Dib
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引用次数: 0

摘要

背景:心力衰竭(HF)是住院和死亡的主要原因,对全球卫生保健系统造成了重大负担。肥胖是心衰的重要危险因素,并会增加心脏压力和代谢需求。方法:使用ICD-10代码,研究1999-2020年CDC WONDER数据库中25岁及以上成人HF和HF合并肥胖相关死亡率的数据。计算了每百万人的年龄调整死亡率(AAMR)。结果:从1999年到2020年,成人HF相关死亡的总体AAMR从1627下降到1544 (AAPC: -0.49, 95% CI: -0.63至-0.34),而HF和肥胖的AAMR从1999年的10.7稳步上升到2020年的42.1 (AAPC: 6.23, 95% CI: 5.50至6.82)。从1999年到2020年,两性与hf相关的AAMR总体下降,女性下降更为明显。相比之下,HF和肥胖相关的AAMRs在两性中均显著增加,男性增加更为明显。与hf相关的AAMRs在白人、西班牙裔或拉丁裔、亚洲/太平洋岛民中下降,但在黑人/非裔美国人和美洲印第安人/阿拉斯加原住民中增加,统计学上不显著。从1999年到2020年,HF和肥胖相关的aamr在所有种族中都有所增加,总体AAPC为6.23。在中西部地区观察到HF相关死亡率和HF及肥胖相关率最高。结论:总体而言,可以看到hf相关死亡率呈下降趋势。然而,尽管心衰死亡率普遍下降,但心衰肥胖死亡率的增加令人担忧。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Trends and disparities in heart failure and heart failure with obesity mortality among U.S. adults: A 1999-2020 analysis of geographic, gender, and racial variations using CDC WONDER data.

Trends and disparities in heart failure and heart failure with obesity mortality among U.S. adults: A 1999-2020 analysis of geographic, gender, and racial variations using CDC WONDER data.

Trends and disparities in heart failure and heart failure with obesity mortality among U.S. adults: A 1999-2020 analysis of geographic, gender, and racial variations using CDC WONDER data.

Trends and disparities in heart failure and heart failure with obesity mortality among U.S. adults: A 1999-2020 analysis of geographic, gender, and racial variations using CDC WONDER data.

Background: Heart failure (HF) is a leading cause of hospitalization and mortality, and it poses a significant burden on healthcare systems globally. Obesity is a considerable risk factor for HF and contributes to increased cardiac stress and metabolic demands.

Methods: Data from the CDC WONDER database were examined from 1999-2020 for HF and HF with obesity-related mortality in adults aged 25 years and older at the time of death, using ICD-10 codes. Age-adjusted mortality rates (AAMR) per million persons were calculated.

Results: From 1999 to 2020, the overall AAMR for HF-related deaths in adults declined from 1627 to 1544 (AAPC: -0.49, 95% CI: -0.63 to -0.34), whereas AAMR for HF and obesity rose steadily from 10.7 in 1999 to 42.1 in 2020 (AAPC: 6.23, 95% CI: 5.50 to 6.82). The overall HF-related AAMR for both genders decreased from 1999 to 2020, with a more significant decline in women. In contrast, HF and obesity-related AAMRs significantly increased for both genders, with a more pronounced rise in men. HF-related AAMRs decreased for Whites, Hispanic or Latinos, and Asian/Pacific Islanders but increased statistically insignificantly for Black/African Americans and American Indian/Alaska Natives. HF and obesity-related AAMRs increased across all races from 1999 to 2020, with an overall AAPC of 6.23. The highest HF-associated mortality and HF and obesity-related rates were observed in the Midwest.

Conclusion: Overall, a declining trend in HF-related mortality could be seen. However, the increasing HF-obesity mortality despite a general decrease in HF death is concerning.

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