Enhancing Standardization in the Pediatric Management of Hereditary Polyposis Syndromes.

Hereditary polyposis syndromes are inherited disorders with high malignancy risk. Management entails early genetic testing, structured surveillance, and risk-informed surgical intervention, yet current practice lacks pediatric-specific standardization. We propose targeted solutions: adoption of pediatric-focused protocols, development of decision-support tools for surgery timing, creation of multidisciplinary pediatric centers, inclusion of psychosocial services and standardized transition programs for lifelong care, and investment in genotype-phenotype research and chemoprevention trials. Coordinated efforts are needed to enhance evidence-based, equitable pediatric hereditary polyposis syndrome care. See related article by Kurowski et al., p. 603.