Synthetic data generation with Worley-Perlin diffusion for robust subarachnoid hemorrhage detection in imbalanced CT Datasets.

Purpose: In this paper, we propose a novel generative model to produce high-quality SAH samples, enhancing SAH CT detection performance in imbalanced datasets. Previous methods, such as cost-sensitive learning and previous diffusion models, suffer from overfitting or noise-induced distortion, limiting their effectiveness. Accurate SAH sample generation is crucial for better detection.

Methods: We propose the Worley-Perlin Diffusion Model (WPDM), leveraging Worley-Perlin noise to synthesize diverse, high-quality SAH images. WPDM addresses limitations of Gaussian noise (homogeneity) and Simplex noise (distortion), enhancing robustness for generating SAH images. Additionally, ${\text{WPDM}}_{\text{Fast}}$ optimizes generation speed without compromising quality.

Results: WPDM effectively improved classification accuracy in datasets with varying imbalance ratios. Notably, a classifier trained with WPDM-generated samples achieved an F1-score of 0.857 on a 1:36 imbalance ratio, surpassing the state of the art by 2.3 percentage points.

Conclusion: WPDM overcomes the limitations of Gaussian and Simplex noise-based models, generating high-quality, realistic SAH images. It significantly enhances classification performance in imbalanced settings, providing a robust solution for SAH CT detection.