在危重病人院前实施有创动脉血压监测——一项前瞻性第一年观察分析

IF 3.1 2区 医学 Q1 EMERGENCY MEDICINE
Jakob Ule, Tobias Hüppe, Julian Thiel, Ulrich Berwanger, Thomas Schlechtriemen, David Conrad, Benedikt Merscher
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引用次数: 0

摘要

背景:低血压暴露与发病率和死亡率增加有关。有创血压(IBP)测量可能优于无创血压测量在检测低血压。IBP的可行性在院前护理选定的病人由专门的救援队已被证明。因此,我们检验了这样一个假设,即院前IBP测量在德国急救系统中由接触危重病人有限的急救小组实施是可行的。方法:采用两辆急诊医师车进行单中心研究。IBP测量的适应症是需要气道管理、儿茶酚胺治疗或液体复苏的成年人。IBP采用直接或Seldinger技术。医生记录了穿刺次数、穿刺部位和穿刺技术。尝试IBP的患者在前三天就诊并报告并发症。如果急诊医生决定不实施IBP,他们会记录一个原因。对数据进行分析,以发现尝试IBP和不尝试IBP以及IBP成功和失败之间的操作差异。采用多元线性回归测量院前IBP尝试对现场时间的影响。结果:在研究期间,发生了3887起紧急事件,其中2.8% (n = 108)符合IBP标准。IBP的原因是儿茶酚胺治疗(74%)、气道管理(73%)和液体复苏(51%)。68例(63%)符合IBP标准的患者接受了IBP尝试,成功率为88%。虽然难以取出(p = 0.002)和较长的运输时间(p = 0.009)与IBP尝试率高相关,但在养老院进行IBP尝试的次数较少(p = 0.002)。不执行IBP的最常见原因是运输优先级和穿刺条件差。多元回归分析显示,IBP尝试使现场时间延长7.4 min (p = 0.013)。结论:院前IBP可以安全地进行,即使是对危重患者接触有限的团队,在广泛的适应症中失败率和并发症发生率都很低。基于这些数据,IBP测量将现场时间延长了7.5分钟。即使接触危重病人很少,如果有指征,团队也应考虑实施IBP。试验注册:该研究是PHINIABP(院前侵入性与非侵入性血压)研究的一部分,已在德国临床试验(ID DRKS00030477)注册,并由地区伦理委员会批准(Ärztekammer Saarland, saarbr cken, Germany,识别号158/22,2022年9月13日)。获得患者或其法定代理人的书面知情同意。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Implementing prehospital invasive arterial blood pressure monitoring in critically ill patients-a prospective observational first year analysis.

Implementing prehospital invasive arterial blood pressure monitoring in critically ill patients-a prospective observational first year analysis.

Background: Exposure to hypotension is linked to increased morbidity and mortality. Invasive blood pressure (IBP) measurement might be superior to non-invasive blood pressure measurement in detecting hypotension. The feasibility of IBP in prehospital care for selected patients by specialized rescue teams has been demonstrated. Therefore, we tested the hypothesis that the implementation of prehospital IBP measurement is feasible in a German emergency system by emergency teams with limited exposure to critically ill patients.

Methods: This single center study was conducted with two emergency physicians vehicles. Indications for IBP measurement were adults requiring airway management, catecholamine therapy or fluid resuscitation. IBP was performed using either direct or Seldinger technique. Physicians recorded the puncture attempts, cannulation sites, and techniques. Patients with IBP attempt were visited the first three days to report complications. Emergency physicians documented a reason if they decided not to perform IBP. Data were analyzed to find operational differences between IBP attempts and no IBP attempts and IBP success and failure. Multiple linear regression was used to measure the influence of prehospital IBP attempts on the on-scene time.

Results: During the study period, 3887 emergency responses occurred, with 2.8% (n = 108) meeting IBP criteria. Reasons for an IBP were catecholamine therapy (74%), airway management (73%) and fluid resuscitation (51%). 68 (63%) of the patients meeting IBP criteria received an IBP attempt with a success rate of 88%. While difficult extrication (p = 0.002) and longer transportation time (p = 0.009) were associated with a high IBP attempt rate, IBP attempts in nursing homes were less often performed (p = 0.002). Most common reason for not performing IBP was a transport priority and poor puncturing condition. Multiple regression analysis showed IBP attempts prolonged the on-scene time by 7.4 min (p = 0.013).

Conclusions: Prehospital IBP can be performed safely even by teams with limited exposure to critically ill patients, with low failure and complication rates across a wide range of indications. Based on these data, IBP measurement prolonged the on-scene time by 7.5 min. Even though exposure to critically ill patients is rare, teams should consider performing an IBP if indicated.

Trial registration: Study was a part of the PHINIABP (PreHospital Invasive vs. Non-Invasive Blood Pressure) study and was registered with German Clinical Trials (ID DRKS00030477) and approved by the regional ethics committee (Ärztekammer Saarland, Saarbrücken, Germany, Identification Number 158/22, September 13, 2022). Written informed consent was obtained from patients or their legal representatives.

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来源期刊
CiteScore
6.10
自引率
6.10%
发文量
57
审稿时长
6-12 weeks
期刊介绍: The primary topics of interest in Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (SJTREM) are the pre-hospital and early in-hospital diagnostic and therapeutic aspects of emergency medicine, trauma, and resuscitation. Contributions focusing on dispatch, major incidents, etiology, pathophysiology, rehabilitation, epidemiology, prevention, education, training, implementation, work environment, as well as ethical and socio-economic aspects may also be assessed for publication.
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