[比萨综合征伴侧结肠合并双侧慢性硬膜下血肿:前庭周围功能减退1例]。

Q4 Medicine
Clinical Neurology Pub Date : 2025-09-25 Epub Date: 2025-08-22 DOI:10.5692/clinicalneurol.cn-002130
Motomi Arai
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引用次数: 0

摘要

一名88岁女性,既往有两次眩晕病史,在使用普瑞巴林治疗四肢远端严重刺痛约4个月后,出现轻微的头部向左倾斜。两个月后(第1天),她头部受伤,但没有失去意识。第22天,患者站立时出现头部剧烈左侧屈。她的步态逐渐恶化,并于第38天来到我们的诊所。神经学检查显示轻度意识障碍,头部和躯干明显向左倾斜。颅脑MRI显示双侧慢性硬膜下血肿,无轴内病变,包括脑干或小脑。手术后,头部和躯干的异常姿势迅速得到解决。水平方向固定,右跳动性眼球震颤,提示左侧前庭功能减退。由于前庭功能减退和普瑞巴林的不良反应引起的细微体位失衡可能被硬膜下血肿代偿,导致明显的颈椎和躯干倾斜。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Pisa syndrome with laterocollis associated with bilateral chronic subdural hematomas: a case report with reference to peripheral vestibular hypofunction].

An 88-year-old woman with a history of two prior episodes of vertigo developed a mild leftward head tilt approximately four months after initiating pregabalin for severe tingling in the distal extremities. Two months later (day 1), she sustained a head injury without loss of consciousness. On day 22, she acutely developed leftward lateral flexion of the head while standing. Her gait progressively deteriorated, and she presented to our clinic on day 38. Neurological examination revealed mild disturbance of consciousness and marked leftward tilt of the head and trunk. Cranial MRI demonstrated bilateral chronic subdural hematomas without intra-axial lesions, including in the brainstem or cerebellum. Following surgical evacuation, the abnormal posture of the head and trunk resolved promptly. A horizontal, direction-fixed, right-beating nystagmus was observed, suggesting left-sided vestibular hypofunction. Subtle postural imbalance due to vestibular hypofunction and adverse effects of pregabalin may have been decompensated by the subdural hematomas, resulting in the pronounced cervical and truncal tilt.

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来源期刊
Clinical Neurology
Clinical Neurology Medicine-Neurology (clinical)
CiteScore
0.30
自引率
0.00%
发文量
147
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