阻塞性睡眠呼吸暂停患者房颤和其他心律失常的系统和机会性筛查:一项前瞻性、单中心、横断面研究

IF 2.8 3区 医学 Q2 PHARMACOLOGY & PHARMACY
Therapeutic Advances in Chronic Disease Pub Date : 2025-08-23 eCollection Date: 2025-01-01 DOI:10.1177/20406223251348336
Tachawut Tiensuntisook, Voravut Rungpradubvong, Naruepat Sangpornsuk, Mananchaya Thapanasuta, Ronpichai Chokesuwattanaskul, Somchai Prechawat, Nattapong Jaimchariyatam
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引用次数: 0

摘要

背景:阻塞性睡眠呼吸暂停(OSA)患者可能是房颤(AF)的高危人群,但在这一人群中进行房颤早期筛查的益处,包括通过筛查检测到的房颤患病率的数据仍然有限。目的:本研究通过三种筛查方法评估OSA患者房颤的患病率,旨在确定最有效的方法,以及在该人群中早期发现房颤的潜在益处。设计:前瞻性、单中心、横断面研究。方法:本研究使用三种筛查方法评估房颤患病率:常规就诊时通过脉搏进行机会性筛查,手持式心电图(EKG)系统筛查,以及多导睡眠描记术期间的EKG。分析还包括筛查阳性的抗凝患者比例和其他非房颤心律失常的患病率。结果:共纳入201例OSA患者,平均年龄46岁,平均CHA2DS2-VASc评分为1分。脉搏、手持式心电图和多导睡眠描记心电图检测AF的患病率分别为1.5%、2.5%和2.0%,差异无统计学意义(p = 0.933)。所有筛查呈阳性的患者均提示口服抗凝治疗。其他非房颤心律失常的患病率高于一般人群,并且在睡眠中检测心律失常似乎比在清醒时检测更有效,特别是对于房性心动过速。结论:OSA患者房颤患病率在1.5% ~ 2.5%之间,手持式EKG系统筛查发生率最高,但差异无统计学意义。非房颤性心律失常也比一般人群更常见,强调需要更广泛的心律失常监测。需要对OSA高风险人群进行进一步的大规模研究,以证实系统房颤筛查的益处。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Systematic and opportunistic screening for atrial fibrillation and other arrhythmias in patients with obstructive sleep apnea: a prospective, single-center, cross-sectional study.

Systematic and opportunistic screening for atrial fibrillation and other arrhythmias in patients with obstructive sleep apnea: a prospective, single-center, cross-sectional study.

Systematic and opportunistic screening for atrial fibrillation and other arrhythmias in patients with obstructive sleep apnea: a prospective, single-center, cross-sectional study.

Systematic and opportunistic screening for atrial fibrillation and other arrhythmias in patients with obstructive sleep apnea: a prospective, single-center, cross-sectional study.

Background: Patients with obstructive sleep apnea (OSA) may be at high risk for atrial fibrillation (AF), but data on the benefits of early AF screening in this population, including the prevalence of AF detected through such screening, remain limited.

Objectives: This study evaluates the prevalence of AF in OSA patients using three screening methods and aims to identify the most effective approach, as well as the potential benefits of early AF detection in this population.

Design: Prospective, single-center, cross-sectional study.

Methods: This study assessed AF prevalence using three screening methods: opportunistic screening via pulse taking during a routine visit, systematic screening with a handheld electrocardiogram (EKG), and EKG during polysomnography. The analysis also included the proportion of patients with positive screenings who were indicated for anticoagulation and the prevalence of other non-AF arrhythmias.

Results: A total of 201 OSA patients were enrolled, with a mean age of 46 years and a mean CHA2DS2-VASc score of 1. The prevalence of AF was 1.5%, 2.5%, and 2.0% when detected by pulse taking, handheld EKG, and EKG during polysomnography, respectively, with no statistically significant difference (p = 0.933). All patients with positive screenings were indicated for oral anticoagulant therapy. The prevalence of other non-AF arrhythmias was higher than in the general population, and detecting arrhythmias during sleep appeared to be more effective than detecting them while awake, particularly for atrial tachycardia.

Conclusion: The prevalence of AF in OSA patients ranged from 1.5% to 2.5%, with the highest rate observed in handheld EKG systematic screening, though the difference was not statistically significant. Non-AF arrhythmias were also more common than in the general population, highlighting the need for broader arrhythmia surveillance. Further large-scale studies in higher-risk OSA populations are needed to confirm the benefits of systematic AF screening.

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来源期刊
Therapeutic Advances in Chronic Disease
Therapeutic Advances in Chronic Disease Medicine-Medicine (miscellaneous)
CiteScore
6.20
自引率
0.00%
发文量
108
审稿时长
12 weeks
期刊介绍: Therapeutic Advances in Chronic Disease publishes the highest quality peer-reviewed research, reviews and scholarly comment in the drug treatment of all chronic diseases. The journal has a strong clinical and pharmacological focus and is aimed at clinicians and researchers involved in the medical treatment of chronic disease, providing a forum in print and online for publishing the highest quality articles in this area.
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