双侧展神经麻痹:侵袭性乳腺癌伴硬脑膜转移的硬脑膜下收集的一种不寻常表现。

Q3 Medicine
Vijo Wilson, Thomas Vt, Arjun Pr
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引用次数: 0

摘要

乳腺癌的硬脑膜转移并不常见,只有不到5%的继发性颅内肿瘤。作为一种表现,双侧外展神经麻痹是极其罕见的,使本病例具有临床意义。本病例报告强调需要认识到晚期恶性肿瘤患者的不寻常的神经系统表现,并提供及时的诊断和管理。一名53岁晚期乳腺癌女性,表现为进行性头痛、呕吐和视力改变。神经学检查发现双侧直肌麻痹和乳头水肿。磁共振成像(MRI)显示硬膜下收集,厚脑膜增厚,脑转移。在通过皮质类固醇治疗缓解症状后,患者计划进行姑息性化疗以及支持性治疗。延误诊断的因素,特别是社会经济障碍问题,对有效管理此类病例构成重大挑战。这个病例集中在诊断转移性乳腺癌的罕见表现,如双侧外展神经麻痹的挑战。在本病例中,有限的医疗保健、延迟的就诊以及影响患者决策的社会经济因素发挥了重要作用。早期识别非典型症状,特别是有恶性病史的病例,将改善患者的预后。同样,由肿瘤学家、神经学家和姑息治疗专家进行的多学科管理将有助于优化这些病例的管理,提高生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bilateral Abducens Nerve Palsy: An Unusual Manifestation of Subdural Collection in Invasive Breast Cancer with Dural Metastasis.

Dural metastases from breast cancer are uncommon, with fewer than 5% of secondary intracranial tumors. As a presentation, bilateral abducens nerve palsy is extremely rare, making this case clinically significant. This case report emphasizes the need to recognize the unusual neurological manifestations in patients with advanced malignancies and to provide timely diagnosis and management. A 53-year-old woman with advanced breast cancer presented with progressive headaches, vomiting, and vision changes. On neurological examination, bilateral lateral rectus palsy and papilledema were observed. Magnetic resonance imaging (MRI) revealed subdural collection, pachymeningeal thickening, and brain metastases. After symptomatic relief through corticosteroid treatment, the patient was planned for palliative chemotherapy along with supportive treatment. Factors delaying diagnosis, with an emphasis on issues of socioeconomic barriers, pose major challenges to effectively managing such cases. This case focuses on the challenges of diagnosing rare manifestations of metastatic breast cancer like bilateral abducens nerve palsy. Limited access to healthcare, delayed presentations, and the socioeconomic factors influencing patient decisions played a significant role in this case. The early recognition of atypical symptoms, particularly in cases with a malignancy history, will improve patient outcomes. Similarly, multidisciplinary management by oncologists, neurologists, and palliative care specialists will help optimize the management of these cases and enhance the quality of life.

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