{"title":"撤回:SENP2通过TGF-βRI的去氧修饰抑制膀胱癌细胞上皮-间质转化。","authors":"","doi":"10.1002/mc.70038","DOIUrl":null,"url":null,"abstract":"<p><strong>Retraction: </strong>M. Tan, D. Zhang, E. Zhang, D. Xu, Z. Liu, J. Qiu, Y. Fan, and B. Shen, \"SENP2 Suppresses Epithelial-Mesenchymal Transition of Bladder Cancer Cells Through deSUMOylation of TGF-βRI,\" Molecular Carcinogenesis 56, no. 10 (2017): 2332-2341. https://doi.org/10.1002/mc.22687. The above article, published online on 02 June 2017, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by Wiley Periodicals LLC. A third party reported to the journal that image elements in Figure 2E of this article had been duplicated and manipulated from a previously published article by a different group of authors and reporting different experimental conditions (Mani et al. 2007 [https://doi.org/10.1073/pnas.0703900104]). Further investigation by the publisher confirmed this duplication and also detected additional duplications between the T24-Vector panel of Figure 5A and the first panel of Figure 5B, as well as duplication and rotation of image elements in the T24-SENP2 panel of Figure 5A and the third panel of Figure 5B. The authors responded to an inquiry by the publisher and stated that there were no issues of duplication between different articles and that the duplications in Figure 5 may have been caused by errors during image preparation. However, the authors were unable to provide original, unmodified data or images for the experiments reported. The retraction has been agreed to because of the duplication of images from another article, as well as duplication and rotation of images and image elements within the same article, which fundamentally compromises the reported conclusions. The authors have stated their consent to the retraction. The authors disagree with the retraction as they have stated they do not agree that image elements were duplicated in Figure 2E.</p>","PeriodicalId":19003,"journal":{"name":"Molecular Carcinogenesis","volume":" ","pages":""},"PeriodicalIF":3.2000,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"RETRACTION: SENP2 Suppresses Epithelial-Mesenchymal Transition of Bladder Cancer Cells Through deSUMOylation of TGF-βRI.\",\"authors\":\"\",\"doi\":\"10.1002/mc.70038\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Retraction: </strong>M. Tan, D. Zhang, E. Zhang, D. Xu, Z. Liu, J. Qiu, Y. Fan, and B. Shen, \\\"SENP2 Suppresses Epithelial-Mesenchymal Transition of Bladder Cancer Cells Through deSUMOylation of TGF-βRI,\\\" Molecular Carcinogenesis 56, no. 10 (2017): 2332-2341. https://doi.org/10.1002/mc.22687. The above article, published online on 02 June 2017, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by Wiley Periodicals LLC. A third party reported to the journal that image elements in Figure 2E of this article had been duplicated and manipulated from a previously published article by a different group of authors and reporting different experimental conditions (Mani et al. 2007 [https://doi.org/10.1073/pnas.0703900104]). Further investigation by the publisher confirmed this duplication and also detected additional duplications between the T24-Vector panel of Figure 5A and the first panel of Figure 5B, as well as duplication and rotation of image elements in the T24-SENP2 panel of Figure 5A and the third panel of Figure 5B. The authors responded to an inquiry by the publisher and stated that there were no issues of duplication between different articles and that the duplications in Figure 5 may have been caused by errors during image preparation. However, the authors were unable to provide original, unmodified data or images for the experiments reported. The retraction has been agreed to because of the duplication of images from another article, as well as duplication and rotation of images and image elements within the same article, which fundamentally compromises the reported conclusions. The authors have stated their consent to the retraction. The authors disagree with the retraction as they have stated they do not agree that image elements were duplicated in Figure 2E.</p>\",\"PeriodicalId\":19003,\"journal\":{\"name\":\"Molecular Carcinogenesis\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2025-08-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Molecular Carcinogenesis\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/mc.70038\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular Carcinogenesis","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/mc.70038","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
引用本文:谭明,张丹,张恩恩,徐东,刘志杰,邱军,樊勇,沈斌,“通过TGF-βRI的去氧修饰抑制膀胱癌细胞上皮-间质转化”,《分子癌变》,第56期,第2期。10(2017): 2332-2341。https://doi.org/10.1002/mc.22687。上述文章于2017年6月2日在线发表在Wiley在线图书馆(wileyonlinelibrary.com)上,已被Wiley期刊有限责任公司撤回。第三方向该期刊报告称,这篇文章的图2E中的图像元素是由另一组作者复制和篡改的,并报告了不同的实验条件(Mani et al. 2007 [https://doi.org/10.1073/pnas.0703900104]])。出版商进一步调查证实了这一重复,并在图5A的T24-Vector面板和图5B的第一个面板之间发现了额外的重复,以及图5A的T24-SENP2面板和图5B的第三个面板中图像元素的重复和旋转。作者回应了出版商的询问,并表示不同文章之间不存在重复的问题,图5中的重复可能是由于图像准备过程中的错误造成的。然而,作者无法为所报道的实验提供原始的、未经修改的数据或图像。由于另一篇文章的图像重复,以及同一篇文章中图像和图像元素的重复和旋转,这从根本上损害了报告的结论,因此同意撤回。作者已声明同意撤稿。作者不同意撤稿,因为他们已经声明他们不同意图2E中重复的图像元素。
RETRACTION: SENP2 Suppresses Epithelial-Mesenchymal Transition of Bladder Cancer Cells Through deSUMOylation of TGF-βRI.
Retraction: M. Tan, D. Zhang, E. Zhang, D. Xu, Z. Liu, J. Qiu, Y. Fan, and B. Shen, "SENP2 Suppresses Epithelial-Mesenchymal Transition of Bladder Cancer Cells Through deSUMOylation of TGF-βRI," Molecular Carcinogenesis 56, no. 10 (2017): 2332-2341. https://doi.org/10.1002/mc.22687. The above article, published online on 02 June 2017, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by Wiley Periodicals LLC. A third party reported to the journal that image elements in Figure 2E of this article had been duplicated and manipulated from a previously published article by a different group of authors and reporting different experimental conditions (Mani et al. 2007 [https://doi.org/10.1073/pnas.0703900104]). Further investigation by the publisher confirmed this duplication and also detected additional duplications between the T24-Vector panel of Figure 5A and the first panel of Figure 5B, as well as duplication and rotation of image elements in the T24-SENP2 panel of Figure 5A and the third panel of Figure 5B. The authors responded to an inquiry by the publisher and stated that there were no issues of duplication between different articles and that the duplications in Figure 5 may have been caused by errors during image preparation. However, the authors were unable to provide original, unmodified data or images for the experiments reported. The retraction has been agreed to because of the duplication of images from another article, as well as duplication and rotation of images and image elements within the same article, which fundamentally compromises the reported conclusions. The authors have stated their consent to the retraction. The authors disagree with the retraction as they have stated they do not agree that image elements were duplicated in Figure 2E.
期刊介绍:
Molecular Carcinogenesis publishes articles describing discoveries in basic and clinical science of the mechanisms involved in chemical-, environmental-, physical (e.g., radiation, trauma)-, infection and inflammation-associated cancer development, basic mechanisms of cancer prevention and therapy, the function of oncogenes and tumors suppressors, and the role of biomarkers for cancer risk prediction, molecular diagnosis and prognosis.