单纯腰椎减压能改善背痛吗?

IF 1.7 4区 医学 Q3 CLINICAL NEUROLOGY
David J Mazur-Hart, Christian G Lopez Ramos, Joseph G Nugent, Brannan E O'Neill, Barry Cheaney, Hanne A Gehling, Jamila Godil, Brandi W Pang, Arilene Novak, James T Obayashi, Travis C Philipp, Clifford Lin, Jung U Yoo, Christina H Wright, James M Wright, Donald A Ross, Josiah N Orina, Won Hyung A Ryu
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引用次数: 0

摘要

研究设计:对某学术机构前瞻性收集的数据库进行回顾性队列研究。目的:(1)评估减压治疗神经源性跛行或神经根病后腰痛(LBP)是否得到改善;(2)使用最小绝对收缩和选择操作者(LASSO)方法确定腰痛改善的术前预测因素;(3)制定一个试点nomogram来指导临床计划和术后预期。背景资料概述:腰痛是退行性腰椎疾病患者的常见主诉。通常,腰痛被认为是减压的禁忌症。有趣的是,腰椎管狭窄症(LSS)患者报告在减压治疗神经源性跛行或神经根病后LBP得到改善。方法:对2017 ~ 2020年行LSS无融合减压手术的患者进行分析。排除有肿瘤、感染、既往融合或问卷不完整的患者。评估患者报告的结果测量(PROMs)、临床变量和放射学变量。在12个月的随访中,将LBP达到最小临床重要差异(MCID)的患者与未达到最小临床重要差异(MCID)的患者进行比较。采用LASSO方法识别相关预测变量。结果:共分析了176例患者。大多数患者因背痛达到MCID (n=109, 61.9%)。基线临床和放射学变量具有可比性。在背部疼痛中达到MCID的患者术前疼痛明显增加,在PROMs中残疾程度也更大。ML识别年龄、BMI、VAS-B、ODI总分值、EQ-5D、promise - p、promise -m、CCI等相关变量,准确预测术后12个月有意义改善的患者(AUROC=0.832)。结论:大多数患者在LSS减压后LBP有显著改善。改善者术前疼痛评分和残疾指标较高。背部疼痛不应成为无融合减压术的禁忌症。开发了一种试验版本的预测图,用于术前临床访问,可以指导临床管理和外科医生/患者的期望。证据等级:三级。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Does Back Pain Improve Following Lumbar Decompression Alone?

Study design: Retrospective cohort study of a prospectively collected database at an academic institution.

Objective: (1) Evaluate if low back pain (LBP) improves following decompression for neurogenic claudication or radiculopathy, (2) use the least absolute shrinkage and selection operator (LASSO) methodology to identify preoperative predictors for improvement in LBP, and (3) develop a pilot nomogram to guide clinical planning and postoperative expectations.

Summary of background data: LBP is a common complaint for patients with degenerative lumbar spine disease. Often, LBP is considered a contraindication to decompression. Anecdotally, patients with lumbar spinal stenosis (LSS) report improvements in LBP following decompression for neurogenic claudication or radiculopathy.

Methods: Patients were analyzed that had decompressive surgery without fusion for LSS from 2017 to 2020. Patients were excluded with a tumor, infection, prior fusion, or incomplete questionnaires. Patient-reported outcome measures (PROMs), clinical variables, and radiographic variables were evaluated. Patients who achieved minimal clinically important difference (MCID) in LBP were compared with those who did not at 12-month follow-up. LASSO methodology was used to identify related predictive variables.

Results: One hundred seventy-six patients were analyzed. The majority reached MCID for back pain (n=109, 61.9%). Baseline clinical and radiographic variables were comparable. Patients who achieved MCID in back pain had significantly higher preoperative pain and greater disability on PROMs. ML identified the related variables of age, BMI, VAS-B, ODI total tertile, EQ-5D, PROMIS-P, PROMIS-M, and CCI to accurately predict who will reach meaningful improvement at 12-months postoperatively (AUROC=0.832).

Conclusions: The majority experienced significant improvements in LBP following decompression for LSS. Improvers had higher preoperative pain scores and measures of disability. Back pain should not be a contraindication to decompression without fusion. A pilot version of a predictive nomogram was developed to be used in the preoperative clinic visit that can guide clinical management and surgeon/patient expectations.

Level of evidence: Level III.

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来源期刊
Clinical Spine Surgery
Clinical Spine Surgery Medicine-Surgery
CiteScore
3.00
自引率
5.30%
发文量
236
期刊介绍: Clinical Spine Surgery is the ideal journal for the busy practicing spine surgeon or trainee, as it is the only journal necessary to keep up to date with new clinical research and surgical techniques. Readers get to watch leaders in the field debate controversial topics in a new controversies section, and gain access to evidence-based reviews of important pathologies in the systematic reviews section. The journal features a surgical technique complete with a video, and a tips and tricks section that allows surgeons to review the important steps prior to a complex procedure. Clinical Spine Surgery provides readers with primary research studies, specifically level 1, 2 and 3 studies, ensuring that articles that may actually change a surgeon’s practice will be read and published. Each issue includes a brief article that will help a surgeon better understand the business of healthcare, as well as an article that will help a surgeon understand how to interpret increasingly complex research methodology. Clinical Spine Surgery is your single source for up-to-date, evidence-based recommendations for spine care.
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