预防和恢复粉尘引起的职业性支气管肺疾病的综合策略:范围综述。

IF 2.3 Q3 RESPIRATORY SYSTEM
Alexandr E Gulyayev, Karlygash S Absattarova, Sayagul A Kairgeldina, Raushan S Dosmagambetova, Kanat K Tekebayev, Madina B Baurzhan, Nazym Sagandykova, Gaukhar Sh Dauletova
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引用次数: 0

摘要

背景:职业性支气管肺疾病(obpd)-包括尘肺病、矽肺和职业性copd -仍然是一个紧迫的公共卫生问题,特别是在采矿、冶金和建筑工业密集的地区。由慢性吸入纤维性粉尘引起,这些病症通常在晚期才被诊断出来,导致不可逆的肺损伤和工作能力下降。方法:使用Arksey和O'Malley框架进行范围审查,并使用乔安娜布里格斯研究所的方法进行改进。按照PRISMA-ScR指南,我们检索了PubMed、Scopus和灰色文献,检索了2014年至2024年的出版物。在筛选1761份记录和全文综述后,最终的综合纳入了9项研究,包括2项系统综述、2项叙述性文献综述和5项观察性研究。结果:确定的关键危险因素包括长期暴露于二氧化硅和煤尘、吸烟和遗传易感性。诊断延迟归因于未充分使用高分辨率CT和呼出一氧化氮分析。一些研究强调了氧化应激和炎症标志物(如IL-6、TNF-α)的诊断价值。营养康复和富含多酚的草药治疗与呼吸功能和生活质量的改善有关。然而,这些战略仍未得到充分利用,特别是在资源匮乏的环境中。结论:迫切需要一种协调的、生物标志物驱动的方法,将早期诊断、粉尘暴露控制和量身定制的康复结合起来。多学科模式可以减轻obpd的临床和社会经济负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

An Integrated Strategy for Preventing and Rehabilitating Dust-Induced Occupational Bronchopulmonary Diseases: A Scoping Review.

An Integrated Strategy for Preventing and Rehabilitating Dust-Induced Occupational Bronchopulmonary Diseases: A Scoping Review.

An Integrated Strategy for Preventing and Rehabilitating Dust-Induced Occupational Bronchopulmonary Diseases: A Scoping Review.

An Integrated Strategy for Preventing and Rehabilitating Dust-Induced Occupational Bronchopulmonary Diseases: A Scoping Review.

Background: Occupational bronchopulmonary diseases (OBPDs)-including pneumoconiosis, silicosis, and occupational COPD-remain a pressing public health issue, especially in regions with intensive mining, metallurgy, and construction industries. Caused by chronic inhalation of fibrogenic dusts, these conditions are often diagnosed at late stages, resulting in irreversible lung damage and diminished work capacity.

Methods: A scoping review was performed using the Arksey and O'Malley framework, with methodological refinements from the Joanna Briggs Institute. Following PRISMA-ScR guidelines, we searched PubMed, Scopus, and gray literature for publications from 2014 to 2024. After screening 1761 records and full-text review, nine studies were included in the final synthesis, comprising two systematic reviews, two narrative literature reviews, and five observational studies.

Results: Key risk factors identified included prolonged exposure to silica and coal dust, tobacco use, and genetic susceptibility. Diagnostic delays were attributed to the underuse of high-resolution CT and exhaled nitric oxide analysis. Several studies highlighted the diagnostic value of oxidative stress and inflammatory markers (e.g., IL-6, TNF-α). Nutritional rehabilitation and polyphenol-enriched herbal therapies were associated with improved respiratory function and quality of life. However, these strategies remain underutilized, particularly in low-resource settings.

Conclusions: A coordinated, biomarker-driven approach integrating early diagnosis, dust exposure control, and tailored rehabilitation is urgently needed. Multidisciplinary models may reduce the clinical and socioeconomic burden of OBPDs.

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来源期刊
Advances in respiratory medicine
Advances in respiratory medicine RESPIRATORY SYSTEM-
CiteScore
2.60
自引率
0.00%
发文量
90
期刊介绍: "Advances in Respiratory Medicine" is a new international title for "Pneumonologia i Alergologia Polska", edited bimonthly and addressed to respiratory professionals. The Journal contains peer-reviewed original research papers, short communications, case-reports, recommendations of the Polish Respiratory Society concerning the diagnosis and treatment of lung diseases, editorials, postgraduate education articles, letters and book reviews in the field of pneumonology, allergology, oncology, immunology and infectious diseases. "Advances in Respiratory Medicine" is an open access, official journal of Polish Society of Lung Diseases, Polish Society of Allergology and National Research Institute of Tuberculosis and Lung Diseases.
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