{"title":"垂体激素替代","authors":"Maria Michaelidou, Shaishav S Dhage","doi":"10.1016/j.mpmed.2025.06.002","DOIUrl":null,"url":null,"abstract":"<div><div>Hypopituitarism is associated with increased morbidity and mortality. Hormone replacement therapies are available for the effective treatment of anterior pituitary deficiencies of growth hormone, adrenocorticotropic hormone, thyroid-stimulating hormone, luteinizing hormone and follicle-stimulating hormone secretion. The posterior pituitary antidiuretic hormone can also be replaced. The aim of replacement therapy is to mimic as far as possible the normal physiology of the hormone and to avoid over-treatment. Currently available hormone preparations and their advantages and disadvantages are discussed.</div></div>","PeriodicalId":74157,"journal":{"name":"Medicine (Abingdon, England : UK ed.)","volume":"53 9","pages":"Pages 574-578"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pituitary hormone replacement\",\"authors\":\"Maria Michaelidou, Shaishav S Dhage\",\"doi\":\"10.1016/j.mpmed.2025.06.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Hypopituitarism is associated with increased morbidity and mortality. Hormone replacement therapies are available for the effective treatment of anterior pituitary deficiencies of growth hormone, adrenocorticotropic hormone, thyroid-stimulating hormone, luteinizing hormone and follicle-stimulating hormone secretion. The posterior pituitary antidiuretic hormone can also be replaced. The aim of replacement therapy is to mimic as far as possible the normal physiology of the hormone and to avoid over-treatment. Currently available hormone preparations and their advantages and disadvantages are discussed.</div></div>\",\"PeriodicalId\":74157,\"journal\":{\"name\":\"Medicine (Abingdon, England : UK ed.)\",\"volume\":\"53 9\",\"pages\":\"Pages 574-578\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medicine (Abingdon, England : UK ed.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1357303925001355\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicine (Abingdon, England : UK ed.)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1357303925001355","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Hypopituitarism is associated with increased morbidity and mortality. Hormone replacement therapies are available for the effective treatment of anterior pituitary deficiencies of growth hormone, adrenocorticotropic hormone, thyroid-stimulating hormone, luteinizing hormone and follicle-stimulating hormone secretion. The posterior pituitary antidiuretic hormone can also be replaced. The aim of replacement therapy is to mimic as far as possible the normal physiology of the hormone and to avoid over-treatment. Currently available hormone preparations and their advantages and disadvantages are discussed.
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