Successful Resection of Mediastinal Paraganglioma in an Adult After a Fontan Procedure

Paraganglioma is a rare neuroendocrine tumor commonly located in the abdomen, head, and neck but rarely in the mediastinum. An association between the Fontan procedure and paragangliomas has been suggested. We report the case of a 28-year-old female patient incidentally diagnosed with a mediastinal paraganglioma at hypertension evaluation during cardiac catheterization post-Fontan procedure. We performed a preoperative right pulmonary artery occlusion test to ensure safe 1-lung ventilation. The tumor’s feeding vessels were embolized to minimize intraoperative blood loss. This case demonstrates successful resection of a mediastinal paraganglioma in a patient with Fontan circulation, using careful preoperative preparation and tumor embolization.