在老年人中支持苯二氮卓类药物处方的障碍和促进因素:对欧洲非医师医疗保健专业人员的调查

IF 3.3 4区 医学 Q2 PHARMACOLOGY & PHARMACY
Vladyslav Shapoval, Perrine Evrard, François-Xavier Sibille, María López-Toribio, Olivia Dalleur, Carole E. Aubert, Lucy Bolt, Vagioula Tsoutsi, Maria Ntafouli, Laura Fernández Maldonado, Ramon Miralles, Adam Wichniak, Katarzyna Gustavsson, Torgeir Bruun Wyller, Enrico Callegari, Jeremy M. Grimshaw, Justin Presseau, Séverine Henrard, Anne Spinewine
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引用次数: 0

摘要

虽然医生主要负责苯二氮卓受体激动剂(BZRA)的处方,非医生医疗保健专业人员(HCPs)可以支持处方。本研究探讨了非医师HCPs开具BZRA处方的障碍和推动因素。我们使用基于理论领域框架(TDF)的问卷调查了六个欧洲国家在医院工作的258名HCPs(63.2%的护士)。逻辑回归评估了TDF域与BZRA处方的支持意图和常规参与之间的关联。主要障碍(平均为3的TDF项目)存在于目标(相互竞争的优先事项)、环境背景和资源(时间和人员缺乏)以及社会影响(患者不情愿)领域。五个TDF域与更强的支持描述意愿相关:社会/职业角色和身份(OR, 3.08; 95% CI, 1.77-5.46);对结果的信念(OR, 1.91; 95% CI, 1.07-3.34);记忆、注意力和决策处理(OR, 1.80; 95% CI, 1.16-2.82);推广替代品的意向(OR, 1.63; 95% CI, 1.07-2.49);和强化(OR, 1.57; 95% CI, 1.08-2.29)。知识是唯一与常规BZRA描述支持相关的领域(OR, 1.16; 95% CI, 1.06-1.27)。不同类别的HCP面临类似的主要障碍,但不同类别和国家的障碍有所不同。具体情况下,有针对性的干预措施可能会加强对BZRA处方的支持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Barriers to and Enablers of Supporting Deprescribing Benzodiazepines in Older Adults: A Survey of European Nonphysician Healthcare Professionals

Barriers to and Enablers of Supporting Deprescribing Benzodiazepines in Older Adults: A Survey of European Nonphysician Healthcare Professionals

Although physicians are primarily responsible for Benzodiazepine Receptor Agonist (BZRA) deprescribing, nonphysician healthcare professionals (HCPs) can support deprescribing. This study explored barriers to and enablers of BZRA deprescribing among nonphysician HCPs. We surveyed 258 HCPs (63.2% nurses) working in hospital settings across six European countries using a questionnaire based on the Theoretical Domain Framework (TDF). Logistic regression assessed associations between TDF domains and both intentions to support and routine engagement in BZRA deprescribing. Major barriers (TDF items with mean < 3) were found in the goals (competing priorities), environmental context and resources (time and staff lack) and social influences (patient reluctance) domains. Five TDF domains were associated with a stronger intention to support deprescribing: social/professional role and identity (OR, 3.08; 95% CI, 1.77–5.46); beliefs about consequences (OR, 1.91; 95% CI, 1.07–3.34); memory, attention and decision processing (OR, 1.80; 95% CI, 1.16–2.82); intention to promote alternatives (OR, 1.63; 95% CI, 1.07–2.49); and reinforcement (OR, 1.57; 95% CI, 1.08–2.29). Knowledge was the only domain associated with routine BZRA deprescribing support (OR, 1.16; 95% CI, 1.06–1.27). Different categories of HCPs face similar major barriers, but barriers vary across HCP categories and countries. Context-specific, targeted interventions may enhance support for BZRA deprescribing.

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来源期刊
CiteScore
5.60
自引率
6.50%
发文量
126
审稿时长
1 months
期刊介绍: Basic & Clinical Pharmacology and Toxicology is an independent journal, publishing original scientific research in all fields of toxicology, basic and clinical pharmacology. This includes experimental animal pharmacology and toxicology and molecular (-genetic), biochemical and cellular pharmacology and toxicology. It also includes all aspects of clinical pharmacology: pharmacokinetics, pharmacodynamics, therapeutic drug monitoring, drug/drug interactions, pharmacogenetics/-genomics, pharmacoepidemiology, pharmacovigilance, pharmacoeconomics, randomized controlled clinical trials and rational pharmacotherapy. For all compounds used in the studies, the chemical constitution and composition should be known, also for natural compounds.
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