{"title":"肾移植患者心理困扰轨迹及影响因素的纵向研究:一项潜在类别分析研究","authors":"Xiaoting Zheng, Xingwang Yao","doi":"10.1111/ctr.70296","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Introduction</h3>\n \n <p>Although kidney transplantation confers substantial benefits, patients also exhibit varying levels of psychological distress attributable to multiple factors, with significant heterogeneity observed in their trajectories of change.</p>\n </section>\n \n <section>\n \n <h3> Objectives</h3>\n \n <p>This study investigates latent heterogeneous trajectories of psychological distress in kidney transplant recipients (KTRs) from pre-transplantation to 6 months postoperatively. It tests the core hypothesis that high Neuroticism (N) and Psychoticism (P) scores serve as key distinguishing predictors of these trajectory classes. The analysis also explores the influence of sociodemographic and clinical factors on class membership. By elucidating distress patterns and their underlying drivers, this research aims to facilitate early identification of high-risk patients and inform the development of personalized psychological interventions, ultimately improving treatment adherence and long-term quality of life.</p>\n </section>\n \n <section>\n \n <h3> Materials and Methods</h3>\n \n <p>A convenience sampling method was used to select 326 kidney transplant patients from the kidney transplant department of a tertiary hospital in Changsha, Hunan Province, from September 2022 to August 2024 as the research subjects. We conducted a cross-sectional survey design by using three standardized instruments: Sociodemographic variables, Eysenck Personality Questionnaire Short Scale-Chinese, and Psychological Distress Thermometer (DT) were collected at four time points: preoperative (T<sub>0</sub>), postoperative 1 week (T<sub>1</sub>), 1 month (T<sub>2</sub>), and 6 months (T<sub>3</sub>). Using a latent variable growth model to identify the developmental trajectory of psychological distress and explore its influencing factors.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Three heterogeneous psychological distress trajectory classes were identified. Membership in these classes was significantly associated with the clinical course of illness, household income, and personality traits.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>Psychological distress in KTRs exhibits significant population heterogeneity. Clinicians can utilize patients' distress trajectory patterns and temperament characteristics to implement personalized care protocols, thereby reducing distress levels.</p>\n </section>\n </div>","PeriodicalId":10467,"journal":{"name":"Clinical Transplantation","volume":"39 9","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Longitudinal Study on Psychological Distress Trajectory and Influencing Factors of Kidney Transplant Patients: A Potential Category Analysis Study\",\"authors\":\"Xiaoting Zheng, Xingwang Yao\",\"doi\":\"10.1111/ctr.70296\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Introduction</h3>\\n \\n <p>Although kidney transplantation confers substantial benefits, patients also exhibit varying levels of psychological distress attributable to multiple factors, with significant heterogeneity observed in their trajectories of change.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Objectives</h3>\\n \\n <p>This study investigates latent heterogeneous trajectories of psychological distress in kidney transplant recipients (KTRs) from pre-transplantation to 6 months postoperatively. It tests the core hypothesis that high Neuroticism (N) and Psychoticism (P) scores serve as key distinguishing predictors of these trajectory classes. The analysis also explores the influence of sociodemographic and clinical factors on class membership. By elucidating distress patterns and their underlying drivers, this research aims to facilitate early identification of high-risk patients and inform the development of personalized psychological interventions, ultimately improving treatment adherence and long-term quality of life.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Materials and Methods</h3>\\n \\n <p>A convenience sampling method was used to select 326 kidney transplant patients from the kidney transplant department of a tertiary hospital in Changsha, Hunan Province, from September 2022 to August 2024 as the research subjects. We conducted a cross-sectional survey design by using three standardized instruments: Sociodemographic variables, Eysenck Personality Questionnaire Short Scale-Chinese, and Psychological Distress Thermometer (DT) were collected at four time points: preoperative (T<sub>0</sub>), postoperative 1 week (T<sub>1</sub>), 1 month (T<sub>2</sub>), and 6 months (T<sub>3</sub>). Using a latent variable growth model to identify the developmental trajectory of psychological distress and explore its influencing factors.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Three heterogeneous psychological distress trajectory classes were identified. Membership in these classes was significantly associated with the clinical course of illness, household income, and personality traits.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>Psychological distress in KTRs exhibits significant population heterogeneity. Clinicians can utilize patients' distress trajectory patterns and temperament characteristics to implement personalized care protocols, thereby reducing distress levels.</p>\\n </section>\\n </div>\",\"PeriodicalId\":10467,\"journal\":{\"name\":\"Clinical Transplantation\",\"volume\":\"39 9\",\"pages\":\"\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-09-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Transplantation\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/ctr.70296\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"SURGERY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Transplantation","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/ctr.70296","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"SURGERY","Score":null,"Total":0}
Longitudinal Study on Psychological Distress Trajectory and Influencing Factors of Kidney Transplant Patients: A Potential Category Analysis Study
Introduction
Although kidney transplantation confers substantial benefits, patients also exhibit varying levels of psychological distress attributable to multiple factors, with significant heterogeneity observed in their trajectories of change.
Objectives
This study investigates latent heterogeneous trajectories of psychological distress in kidney transplant recipients (KTRs) from pre-transplantation to 6 months postoperatively. It tests the core hypothesis that high Neuroticism (N) and Psychoticism (P) scores serve as key distinguishing predictors of these trajectory classes. The analysis also explores the influence of sociodemographic and clinical factors on class membership. By elucidating distress patterns and their underlying drivers, this research aims to facilitate early identification of high-risk patients and inform the development of personalized psychological interventions, ultimately improving treatment adherence and long-term quality of life.
Materials and Methods
A convenience sampling method was used to select 326 kidney transplant patients from the kidney transplant department of a tertiary hospital in Changsha, Hunan Province, from September 2022 to August 2024 as the research subjects. We conducted a cross-sectional survey design by using three standardized instruments: Sociodemographic variables, Eysenck Personality Questionnaire Short Scale-Chinese, and Psychological Distress Thermometer (DT) were collected at four time points: preoperative (T0), postoperative 1 week (T1), 1 month (T2), and 6 months (T3). Using a latent variable growth model to identify the developmental trajectory of psychological distress and explore its influencing factors.
Results
Three heterogeneous psychological distress trajectory classes were identified. Membership in these classes was significantly associated with the clinical course of illness, household income, and personality traits.
Conclusions
Psychological distress in KTRs exhibits significant population heterogeneity. Clinicians can utilize patients' distress trajectory patterns and temperament characteristics to implement personalized care protocols, thereby reducing distress levels.
期刊介绍:
Clinical Transplantation: The Journal of Clinical and Translational Research aims to serve as a channel of rapid communication for all those involved in the care of patients who require, or have had, organ or tissue transplants, including: kidney, intestine, liver, pancreas, islets, heart, heart valves, lung, bone marrow, cornea, skin, bone, and cartilage, viable or stored.
Published monthly, Clinical Transplantation’s scope is focused on the complete spectrum of present transplant therapies, as well as also those that are experimental or may become possible in future. Topics include:
Immunology and immunosuppression;
Patient preparation;
Social, ethical, and psychological issues;
Complications, short- and long-term results;
Artificial organs;
Donation and preservation of organ and tissue;
Translational studies;
Advances in tissue typing;
Updates on transplant pathology;.
Clinical and translational studies are particularly welcome, as well as focused reviews. Full-length papers and short communications are invited. Clinical reviews are encouraged, as well as seminal papers in basic science which might lead to immediate clinical application. Prominence is regularly given to the results of cooperative surveys conducted by the organ and tissue transplant registries.
Clinical Transplantation: The Journal of Clinical and Translational Research is essential reading for clinicians and researchers in the diverse field of transplantation: surgeons; clinical immunologists; cryobiologists; hematologists; gastroenterologists; hepatologists; pulmonologists; nephrologists; cardiologists; and endocrinologists. It will also be of interest to sociologists, psychologists, research workers, and to all health professionals whose combined efforts will improve the prognosis of transplant recipients.