烯烃分子间羰基自由基加成研究进展

IF 4.7 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Chemistry Frontiers Pub Date : 2025-08-30 DOI:10.1039/d5qo01045d

Jun Pan, Yuting Feng, Huijun Qian, Leiyang Lv, Zhiping Li

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引用次数: 0

摘要

氧中心自由基是高度活跃的中间体，在自由基介导的有机转化中起着关键作用。羰基氧基自由基是氧中心自由基的一个独特分支，它不仅表现出氧中心自由基的一般反应模式，如氢原子转移（HAT）和β-断裂，而且还表现出其亲电酯基的独特行为。本文综述了近年来通过不同的羰基自由基前体在烯烃分子间加成芳基和烷氧基羰基自由基的研究进展。这些转化突出了新的酯化反应，在这些反应中，醇通常与羧酸、酰氯或酸酐反应。我们的目标是激发对羰基自由基化学的创新酯化反应的进一步探索。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Recent Advances of Intermolecular Carbonyloxy Radicals Addition to Alkenes

Oxygen-centered radicals are highly reactive intermediates that serve as key roles in radical-mediated organic transformations.Carbonyloxy radicals, a distinct subset of oxygen-centered radicals, not only exhibit the general reactivity patterns of oxygencentered species, such as hydrogen atom transfer (HAT) and β-scission, but also demonstrate unique behaviors attributed to their electrophilic ester group. We summarizes recent progress in the intermolecular addition of aryl and alkoxy carbonyloxy radicals to alkenes through different precursors of carbonyloxy radicals in this review. These transformations highlight novel esterafication reactions, in which generally alcohols react with carboxylic acids, acyl chlorides, or acid anhydrides. We aim to inspire further exploration into the innovative esterafication reactions enabled by carbonyloxy radical chemistry.

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来源期刊

Organic Chemistry Frontiers CHEMISTRY, ORGANIC-

CiteScore

7.90

自引率

11.10%

发文量

686

审稿时长

1 months

期刊介绍： Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.