研究果蝇早期发育中单个胚胎的代谢变化

IF 20.8 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Nature metabolism Pub Date : 2025-08-22 DOI:10.1038/s42255-025-01375-x

引用次数: 0

摘要

在动物的早期发育过程中，新陈代谢是动态的。为了研究这一过程，我们开发了一种单胚胎代谢组学和转录组学方法，可以捕获代谢的快速、小规模变化以及它们如何与基因表达协调。我们在果蝇胚胎中展示了这种方法，为理解发育系统生物学提供了宝贵的资源。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Investigating metabolic changes in single embryos during early development in Drosophila

查看原文本刊更多论文

Investigating metabolic changes in single embryos during early development in Drosophila

Metabolism is dynamic during early development in animals. To study this process, we developed a single-embryo metabolomics and transcriptomics method that captures rapid, small-scale changes in metabolism and how they coordinate with gene expression. Our work showcasing this method in Drosophila embryos provides a valuable resource for understanding developmental systems biology.

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来源期刊

Nature metabolism ENDOCRINOLOGY & METABOLISM-

CiteScore

27.50

自引率

2.40%

发文量

170

期刊介绍： Nature Metabolism is a peer-reviewed scientific journal that covers a broad range of topics in metabolism research. It aims to advance the understanding of metabolic and homeostatic processes at a cellular and physiological level. The journal publishes research from various fields, including fundamental cell biology, basic biomedical and translational research, and integrative physiology. It focuses on how cellular metabolism affects cellular function, the physiology and homeostasis of organs and tissues, and the regulation of organismal energy homeostasis. It also investigates the molecular pathophysiology of metabolic diseases such as diabetes and obesity, as well as their treatment. Nature Metabolism follows the standards of other Nature-branded journals, with a dedicated team of professional editors, rigorous peer-review process, high standards of copy-editing and production, swift publication, and editorial independence. The journal has a high impact factor, has a certain influence in the international area, and is deeply concerned and cited by the majority of scholars.