Principle and Application of Novel Negative Air (Oxygen) Ion Storage and Release Products

Negative air ions (NAI) are ions present in the air that enhance blood oxygen absorption and utilization, stimulate metabolism, and modulate mood and nervous system activity. However, the application of NAI has been limited by storage challenges and low concentrations due to the conditions under which they are produced and the nature of the ions themselves. In order to overcome these limitations and develop NAI as a viable method of treatment, we have introduced a novel, highly concentrated NAI prodrug that incorporates NAI into flaxseed oil. This innovative drug can be administered in liquid, semiliquid, and dietary forms. Additionally, we have explored various NAI-related actions and mechanisms, such as the antiaging effects of these drugs through ROS inhibition. Our research has shown that NAI agents can penetrate the brain through the skin and the blood–brain barrier, rapidly reoxygenating cells throughout the body. Particularly, NAI has demonstrated excellent antitumor and cognitive-enhancing properties. These findings have significant implications for the potential of our NAI-based prodrug as a groundbreaking approach in antiaging therapy, providing a novel strategy for enhancing endogenous oxygenation and treating respiratory compromise and beyond.