Leigha A MacNeill, Yudong Zhang, Gina M Giase, Jillian Lee Wiggins, Elizabeth S Norton, Justin D Smith, Matthew M Davis, Julia G Raven, Roshaye B Poleon, Qiongru Yu, Christopher D Smyser, Cynthia E Rogers, Joan L Luby, Norrina B Allen, Lauren S Wakschlag
{"title":"儿童心理健康风险计算器的发展基础。","authors":"Leigha A MacNeill, Yudong Zhang, Gina M Giase, Jillian Lee Wiggins, Elizabeth S Norton, Justin D Smith, Matthew M Davis, Julia G Raven, Roshaye B Poleon, Qiongru Yu, Christopher D Smyser, Cynthia E Rogers, Joan L Luby, Norrina B Allen, Lauren S Wakschlag","doi":"10.1016/j.acap.2025.103128","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To advance clinical utility of an emerging risk calculator for identifying when to worry and when to act when young children show signs of mental health concerns in pediatric care, we: (1) replicate an early childhood mental health risk algorithm (DECIDE); (2) determine preliminary predictive utility of additional child and parenting assets, advancing a strengths-based framework to reduce the likelihood of biased identification.</p><p><strong>Methods: </strong>Data were from two independent studies: The national Future of Families and Child Wellbeing Study (FFCWS; N=2,763) and the regional Mental Health, Earlier Synthetic Cohort study (MHESC; N=323). Predictors were assessed in toddlerhood/early preschool age. Internalizing/externalizing problems were measured in older preschoolers, serving as outcomes. Epidemiologic risk prediction methods were applied to: (1) replicate the DECIDE risk algorithm domains comprised of demographics, child irritability, and adverse childhood experiences; and (2) examine the added predictive utility of child and parenting assets. Predictive utility was based on area under the curve (AUC) and/or the integrated discrimination improvement (IDI).</p><p><strong>Results: </strong>The DECIDE algorithm was replicated in FFCWS and MHESC (AUC=.70 for both studies; IDI=.07 in FFCWS and.06 in MHESC). IDIs indicated predictive utility for child assets beyond the existing DECIDE algorithm in both studies, and for parenting assets in FFCWS.</p><p><strong>Conclusions: </strong>Robust validation of predictive algorithms is critical for assessing generalizability. Reducing bias in early mental health risk algorithms via a strengths-based approach is key to equitable decision-making. This work lays the foundation for implementation of early mental health decision tools in routine care of young children.</p>","PeriodicalId":50930,"journal":{"name":"Academic Pediatrics","volume":" ","pages":"103128"},"PeriodicalIF":2.8000,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Developmental Foundations of a Pediatric Mental Health Risk Calculator for Young Children.\",\"authors\":\"Leigha A MacNeill, Yudong Zhang, Gina M Giase, Jillian Lee Wiggins, Elizabeth S Norton, Justin D Smith, Matthew M Davis, Julia G Raven, Roshaye B Poleon, Qiongru Yu, Christopher D Smyser, Cynthia E Rogers, Joan L Luby, Norrina B Allen, Lauren S Wakschlag\",\"doi\":\"10.1016/j.acap.2025.103128\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To advance clinical utility of an emerging risk calculator for identifying when to worry and when to act when young children show signs of mental health concerns in pediatric care, we: (1) replicate an early childhood mental health risk algorithm (DECIDE); (2) determine preliminary predictive utility of additional child and parenting assets, advancing a strengths-based framework to reduce the likelihood of biased identification.</p><p><strong>Methods: </strong>Data were from two independent studies: The national Future of Families and Child Wellbeing Study (FFCWS; N=2,763) and the regional Mental Health, Earlier Synthetic Cohort study (MHESC; N=323). Predictors were assessed in toddlerhood/early preschool age. Internalizing/externalizing problems were measured in older preschoolers, serving as outcomes. Epidemiologic risk prediction methods were applied to: (1) replicate the DECIDE risk algorithm domains comprised of demographics, child irritability, and adverse childhood experiences; and (2) examine the added predictive utility of child and parenting assets. Predictive utility was based on area under the curve (AUC) and/or the integrated discrimination improvement (IDI).</p><p><strong>Results: </strong>The DECIDE algorithm was replicated in FFCWS and MHESC (AUC=.70 for both studies; IDI=.07 in FFCWS and.06 in MHESC). IDIs indicated predictive utility for child assets beyond the existing DECIDE algorithm in both studies, and for parenting assets in FFCWS.</p><p><strong>Conclusions: </strong>Robust validation of predictive algorithms is critical for assessing generalizability. Reducing bias in early mental health risk algorithms via a strengths-based approach is key to equitable decision-making. This work lays the foundation for implementation of early mental health decision tools in routine care of young children.</p>\",\"PeriodicalId\":50930,\"journal\":{\"name\":\"Academic Pediatrics\",\"volume\":\" \",\"pages\":\"103128\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2025-08-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Academic Pediatrics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.acap.2025.103128\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Academic Pediatrics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.acap.2025.103128","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PEDIATRICS","Score":null,"Total":0}
Developmental Foundations of a Pediatric Mental Health Risk Calculator for Young Children.
Objective: To advance clinical utility of an emerging risk calculator for identifying when to worry and when to act when young children show signs of mental health concerns in pediatric care, we: (1) replicate an early childhood mental health risk algorithm (DECIDE); (2) determine preliminary predictive utility of additional child and parenting assets, advancing a strengths-based framework to reduce the likelihood of biased identification.
Methods: Data were from two independent studies: The national Future of Families and Child Wellbeing Study (FFCWS; N=2,763) and the regional Mental Health, Earlier Synthetic Cohort study (MHESC; N=323). Predictors were assessed in toddlerhood/early preschool age. Internalizing/externalizing problems were measured in older preschoolers, serving as outcomes. Epidemiologic risk prediction methods were applied to: (1) replicate the DECIDE risk algorithm domains comprised of demographics, child irritability, and adverse childhood experiences; and (2) examine the added predictive utility of child and parenting assets. Predictive utility was based on area under the curve (AUC) and/or the integrated discrimination improvement (IDI).
Results: The DECIDE algorithm was replicated in FFCWS and MHESC (AUC=.70 for both studies; IDI=.07 in FFCWS and.06 in MHESC). IDIs indicated predictive utility for child assets beyond the existing DECIDE algorithm in both studies, and for parenting assets in FFCWS.
Conclusions: Robust validation of predictive algorithms is critical for assessing generalizability. Reducing bias in early mental health risk algorithms via a strengths-based approach is key to equitable decision-making. This work lays the foundation for implementation of early mental health decision tools in routine care of young children.
期刊介绍:
Academic Pediatrics, the official journal of the Academic Pediatric Association, is a peer-reviewed publication whose purpose is to strengthen the research and educational base of academic general pediatrics. The journal provides leadership in pediatric education, research, patient care and advocacy. Content areas include pediatric education, emergency medicine, injury, abuse, behavioral pediatrics, holistic medicine, child health services and health policy,and the environment. The journal provides an active forum for the presentation of pediatric educational research in diverse settings, involving medical students, residents, fellows, and practicing professionals. The journal also emphasizes important research relating to the quality of child health care, health care policy, and the organization of child health services. It also includes systematic reviews of primary care interventions and important methodologic papers to aid research in child health and education.