氯化锡（II）介导的氟化醇苯甲酸酯光催化烯烃加氢功能化。

IF 5 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Letters Pub Date : 2025-08-19 DOI:10.1021/acs.orglett.5c03013

Sergey S. Lunkov, Ekaterina V. Malakhova, Vitalij V. Levin and Alexander D. Dilman*,

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引用次数: 0

摘要

介绍了一种烯烃与3,3,3-三氟乳酸酯和双（三氟甲基）取代醇的苯甲酸酯进行氢氟烷基化的方法。该反应是用n -苯基吩噻嗪光催化剂进行的，对官能团有很高的耐受性。该方法的一个主要特点是使用氯化锡/甲苯磺酸作为化学计量还原剂。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Photocatalytic Alkene Hydrofunctionalization with Benzoic Esters of Fluorinated Alcohols Mediated by Tin(II) Chloride

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Photocatalytic Alkene Hydrofunctionalization with Benzoic Esters of Fluorinated Alcohols Mediated by Tin(II) Chloride

A method for the hydrofluoroalkylation of alkenes with the benzoic ester of 3,3,3-trifluorolactate and bis(trifluoromethyl)-substituted alcohols is described. The reaction is performed with N-phenylphenothiazine photocatalyst and has high tolerance toward functional groups. A key feature of the method is the use of tin(II) chloride/toluenesulfonic acid as a stoichiometric reducing agent.

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来源期刊

Organic Letters 化学-有机化学

CiteScore

9.30

自引率

11.50%

发文量

1607

审稿时长

1.5 months

期刊介绍： Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.