含铬丙烯酸合成荧光2-（吡喃[3,2-c]铬-5-基）乙酸

IF 2 3区化学 Q2 CHEMISTRY, ORGANIC

Journal of Heterocyclic Chemistry Pub Date : 2025-07-06 DOI:10.1002/jhet.70008

Sergey V. Efimov, Nikita M. Chernov, Maxim S. Panov, Dmitrii M. Nikolaev, Mikhail N. Ryazantsev, Roman V. Shutov, Igor P. Yakovlev

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引用次数: 0

摘要

研究了一种合成2-（吡喃[3,2-c]铬-5-基）乙酸及其衍生物的简便方法。采用含铬丙烯酸与氰乙酸乙酯anorc反应的方法合成。该方法的特点是：(a)反应条件简单（乙醇，20°C - 25°C，三乙胺作为催化剂），(b)产物的非色谱分离，(C)产率高（高达95%）。所得吡咯[3,2-c]铬在光谱的黄绿色区域（492-554 nm）具有强烈的荧光，并表现出大的斯托克斯位移（高达6300 cm−1）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Synthesis of Fluorescent 2-(Pyrano[3,2-c]chromene-5-yl)Acetic Acids From Chromone-Containing Acrylic Acids

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Synthesis of Fluorescent 2-(Pyrano[3,2-c]chromene-5-yl)Acetic Acids From Chromone-Containing Acrylic Acids

We have developed a convenient method for the synthesis of 2-(pyrano[3,2-c]chromen-5-yl)acetic acids and their derivatives. The synthetic approach is based on the ANRORC reaction of chromone-containing acrylic acids and ethyl cyanoacetate. The features of the method are (a) simple reaction conditions (ethanol, 20°C–25°C, triethylamine as catalyst), (b) non-chromatographic isolation of products, and (c) high yields (up to 95%). The resulting pyrano[3,2-c]chromenes have intense fluorescence in the yellow-green region of the spectrum (492–554 nm) and demonstrate large Stokes shifts (up to 6300 cm⁻¹).

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来源期刊

Journal of Heterocyclic Chemistry 化学-有机化学

CiteScore

5.20

自引率

4.20%

发文量

177

审稿时长

3.9 months

期刊介绍： The Journal of Heterocyclic Chemistry is interested in publishing research on all aspects of heterocyclic chemistry, especially development and application of efficient synthetic methodologies and strategies for the synthesis of various heterocyclic compounds. In addition, Journal of Heterocyclic Chemistry promotes research in other areas that contribute to heterocyclic synthesis/application, such as synthesis design, reaction techniques, flow chemistry and continuous processing, multiphase catalysis, green chemistry, catalyst immobilization and recycling.