Marije C Vink, Rinne M Peters, Bart Van Dooren, Amarens Deen, Liza N Van Steenbergen, B Wim Schreurs, Wierd P Zijlstra
{"title":"大容量医院在脓毒症和无菌翻修全髋关节置换术中的表现并不比小容量医院好:一项基于荷兰关节置换术登记册的再翻修风险和死亡率分析。","authors":"Marije C Vink, Rinne M Peters, Bart Van Dooren, Amarens Deen, Liza N Van Steenbergen, B Wim Schreurs, Wierd P Zijlstra","doi":"10.2340/17453674.2025.44331","DOIUrl":null,"url":null,"abstract":"<p><strong>Background and purpose: </strong> Revision total hip arthroplasty (rTHA) is a complex procedure that may benefit from centralization. We examined the association between annual hospital volume of rTHA and re-revision risk and mortality.</p><p><strong>Methods: </strong> We included all rTHAs between 2007 and 2022 in general hospitals, registered in the Dutch Arthroplasty Register (LROI; n = 12,515). Hospitals were categorized into low (< 25 rTHA/year) or high volume (≥ 25 rTHA/year). Competing-risk analyses and Cox proportional hazard regression analyses were performed to assess implant re-revision and Kaplan-Meier survival analysis for mortality. Results were stratified into septic (permanent Girdlestone, 1-stage, and 2-stage revisions) and aseptic first revisions.</p><p><strong>Results: </strong> 1-stage septic revisions showed a higher risk of re-revision in high-volume hospitals (hazard ratio [HR] 1.6, 95% confidence interval [CI] 1.1-2.4). We found no difference in re-revision risk after DAIR (HR 1.1, CI 0.9-1.3). 2-stage septic revisions were more often performed in high-volume hospitals (5% vs 2%). There was no statistical difference in re-revision rates between hospitals after revision for aseptic loosening (HR 1.1, CI 0.9-1.4), dislocation (HR 1.1, CI 0.9-1.4), and periprosthetic fractures (HR 1.1, CI 0.8-1.5). Mortality showed no differences between groups, neither for septic nor aseptic revisions.</p><p><strong>Conclusion: </strong> There was no difference between high-volume hospitals and low-volume hospitals regarding risk for re-revision after aseptic loosening, dislocation and periprosthetic fracture, and septic DAIR and mortality. In high-volume hospitals, 1-stage septic revisions was associated with a significantly higher re-revision risk. 2-stage revisions are more frequent in high-volume hospitals, indicating more complex pathology.</p>","PeriodicalId":6916,"journal":{"name":"Acta Orthopaedica","volume":"96 ","pages":"625-631"},"PeriodicalIF":2.4000,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357176/pdf/","citationCount":"0","resultStr":"{\"title\":\"High-volume hospitals do not perform better than low-volume hospitals in septic and aseptic revision total hip arthroplasty: an analysis of re-revision risk and mortality based on the Dutch Arthroplasty Register.\",\"authors\":\"Marije C Vink, Rinne M Peters, Bart Van Dooren, Amarens Deen, Liza N Van Steenbergen, B Wim Schreurs, Wierd P Zijlstra\",\"doi\":\"10.2340/17453674.2025.44331\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background and purpose: </strong> Revision total hip arthroplasty (rTHA) is a complex procedure that may benefit from centralization. We examined the association between annual hospital volume of rTHA and re-revision risk and mortality.</p><p><strong>Methods: </strong> We included all rTHAs between 2007 and 2022 in general hospitals, registered in the Dutch Arthroplasty Register (LROI; n = 12,515). Hospitals were categorized into low (< 25 rTHA/year) or high volume (≥ 25 rTHA/year). Competing-risk analyses and Cox proportional hazard regression analyses were performed to assess implant re-revision and Kaplan-Meier survival analysis for mortality. Results were stratified into septic (permanent Girdlestone, 1-stage, and 2-stage revisions) and aseptic first revisions.</p><p><strong>Results: </strong> 1-stage septic revisions showed a higher risk of re-revision in high-volume hospitals (hazard ratio [HR] 1.6, 95% confidence interval [CI] 1.1-2.4). We found no difference in re-revision risk after DAIR (HR 1.1, CI 0.9-1.3). 2-stage septic revisions were more often performed in high-volume hospitals (5% vs 2%). There was no statistical difference in re-revision rates between hospitals after revision for aseptic loosening (HR 1.1, CI 0.9-1.4), dislocation (HR 1.1, CI 0.9-1.4), and periprosthetic fractures (HR 1.1, CI 0.8-1.5). Mortality showed no differences between groups, neither for septic nor aseptic revisions.</p><p><strong>Conclusion: </strong> There was no difference between high-volume hospitals and low-volume hospitals regarding risk for re-revision after aseptic loosening, dislocation and periprosthetic fracture, and septic DAIR and mortality. In high-volume hospitals, 1-stage septic revisions was associated with a significantly higher re-revision risk. 2-stage revisions are more frequent in high-volume hospitals, indicating more complex pathology.</p>\",\"PeriodicalId\":6916,\"journal\":{\"name\":\"Acta Orthopaedica\",\"volume\":\"96 \",\"pages\":\"625-631\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2025-08-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357176/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Orthopaedica\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2340/17453674.2025.44331\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ORTHOPEDICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Orthopaedica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2340/17453674.2025.44331","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0
摘要
背景和目的:翻修全髋关节置换术(rTHA)是一项复杂的手术,可以从集中手术中获益。我们研究了每年rTHA住院量与再次翻修风险和死亡率之间的关系。方法:我们纳入了2007年至2022年间在荷兰关节置换术登记册(LROI;N = 12515)。医院分为低容量(< 25 rTHA/年)和高容量(≥25 rTHA/年)。采用竞争风险分析和Cox比例风险回归分析来评估植入物重新翻修和Kaplan-Meier生存分析的死亡率。结果分为化脓性(永久性Girdlestone、1期和2期修订)和无菌性首次修订。结果:在大容量医院,一期脓毒性翻修显示出更高的再次翻修风险(风险比[HR] 1.6, 95%可信区间[CI] 1.1-2.4)。我们发现DAIR后的再修订风险没有差异(HR 1.1, CI 0.9-1.3)。大容量医院更常进行2期脓毒性修复(5% vs 2%)。无菌性松动(HR 1.1, CI 0.9-1.4)、脱位(HR 1.1, CI 0.9-1.4)和假体周围骨折(HR 1.1, CI 0.8-1.5)翻修后医院间的再次翻修率无统计学差异。两组之间的死亡率没有差异,无论是败血性的还是无菌性的。结论:大容量医院与小容量医院在无菌性松动、脱位和假体周围骨折后再翻修的风险、脓毒性DAIR和死亡率方面无差异。在大容量医院中,一期脓毒症翻修与再次翻修风险显著升高相关。在大容量医院中,两阶段翻修更为常见,表明病理更复杂。
High-volume hospitals do not perform better than low-volume hospitals in septic and aseptic revision total hip arthroplasty: an analysis of re-revision risk and mortality based on the Dutch Arthroplasty Register.
Background and purpose: Revision total hip arthroplasty (rTHA) is a complex procedure that may benefit from centralization. We examined the association between annual hospital volume of rTHA and re-revision risk and mortality.
Methods: We included all rTHAs between 2007 and 2022 in general hospitals, registered in the Dutch Arthroplasty Register (LROI; n = 12,515). Hospitals were categorized into low (< 25 rTHA/year) or high volume (≥ 25 rTHA/year). Competing-risk analyses and Cox proportional hazard regression analyses were performed to assess implant re-revision and Kaplan-Meier survival analysis for mortality. Results were stratified into septic (permanent Girdlestone, 1-stage, and 2-stage revisions) and aseptic first revisions.
Results: 1-stage septic revisions showed a higher risk of re-revision in high-volume hospitals (hazard ratio [HR] 1.6, 95% confidence interval [CI] 1.1-2.4). We found no difference in re-revision risk after DAIR (HR 1.1, CI 0.9-1.3). 2-stage septic revisions were more often performed in high-volume hospitals (5% vs 2%). There was no statistical difference in re-revision rates between hospitals after revision for aseptic loosening (HR 1.1, CI 0.9-1.4), dislocation (HR 1.1, CI 0.9-1.4), and periprosthetic fractures (HR 1.1, CI 0.8-1.5). Mortality showed no differences between groups, neither for septic nor aseptic revisions.
Conclusion: There was no difference between high-volume hospitals and low-volume hospitals regarding risk for re-revision after aseptic loosening, dislocation and periprosthetic fracture, and septic DAIR and mortality. In high-volume hospitals, 1-stage septic revisions was associated with a significantly higher re-revision risk. 2-stage revisions are more frequent in high-volume hospitals, indicating more complex pathology.
期刊介绍:
Acta Orthopaedica (previously Acta Orthopaedica Scandinavica) presents original articles of basic research interest, as well as clinical studies in the field of orthopedics and related sub disciplines. Ever since the journal was founded in 1930, by a group of Scandinavian orthopedic surgeons, the journal has been published for an international audience. Acta Orthopaedica is owned by the Nordic Orthopaedic Federation and is the official publication of this federation.