胎儿快速心律失常:临床实践的最新知识。

IF 1.7 4区 医学 Q2 PEDIATRICS
Translational pediatrics Pub Date : 2025-07-31 Epub Date: 2025-07-17 DOI:10.21037/tp-2025-67
Maria Elisa Martini Albrecht, Sérgio Faria Makabe, Nathalie Jeanne Bravo-Valenzuela, Edward Araujo Júnior
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引用次数: 0

摘要

胎儿心律失常占专科胎儿医学中心所有门诊会诊的10-20%。此外,很明显,速性心律失常占所有此类心律失常的8%。大多数心律失常是良性的,易于控制,但某些速性心律失常需要密切监测,因为有代偿失代偿、进展为心力衰竭伴积液和潜在的胎儿死亡的风险。本研究的目的是描述最常见的胎儿心动过速及其宫内处理。使用胎儿超声/超声心动图,临床医生可以评估心率(HR),胎儿心律,并确定心律模式。鉴别胎儿速性心律失常的类型是至关重要的,因为某些抗心律失常药物对特定的心律失常更有效。尽管在诊断和治疗方面取得了进展,但研究表明,患者数量有限,而且根据当地经验和现有资源的治疗方法种类繁多。胎儿治疗在改善胎儿和产后生活预后方面的潜力已经得到了很好的证明。胎儿心律失常有几种治疗方案,根据医疗团队的经验和实际治疗考虑选择最有效的药物。经胎盘治疗是子宫内使用抗心律失常药物最广泛的途径。总的来说,研究已经证明,在治疗伴有或不伴有胎儿水肿的胎儿室上性心动过速(SVT)方面,氟氯胺和索他洛尔的疗效优于地高辛。氟氯胺可与地高辛合用治疗胎儿上室血栓及水肿。对于持续性室性心动过速(VT),当胎儿心率超过200 bpm时,一线治疗是母体静脉注射镁。此外,重要的是要记住,频率控制是治疗胎儿窦性心律逆转不成功和肺不成熟的选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fetal tachyarrhythmias: current knowledge for clinical practice.

Fetal arrhythmias account for 10-20% of all outpatient consultations in specialized fetal medicine centers. Furthermore, it is evident that tachyarrhythmias account for 8% of all such arrhythmias. Most arrhythmias are benign and easy to manage, but certain tachyarrhythmias require close monitoring due to the risk of decompensation, progression to heart failure with hydrops, and potential fetal death. The aim of this study was to describe the most common fetal tachycardias and their intrauterine management. Using fetal ultrasound/echocardiography, clinicians can assess the heart rate (HR), fetal heart rhythm, and determine rhythm patterns. Differentiating the type of fetal tachyarrhythmia is crucial, as certain antiarrhythmic drugs are more effective for specific arrhythmias. Despite advances in diagnosis and treatment, studies reveal limited numbers of patients, and a wide variety of treatments based on local experience and available resources. The potential of fetal treatment to improve prognosis in both fetal and postnatal life has been well demonstrated. There are several treatment options for fetal tachyarrhythmias, with the most effective medication selected based on the healthcare team's experience and practical treatment considerations. Transplacental therapy is the most widely used route for administering antiarrhythmic drugs in utero. In general, studies have been demonstrated the superior efficacy of flecainide and sotalol in comparison to digoxin in the treatment of fetal supraventricular tachycardia (SVT), with or without fetal edema. Flecainide can be used in combination with digoxin to treat SVT and hydrops in fetuses. For sustained ventricular tachycardia (VT), first-line treatment is maternal intravenous magnesium when fetal HR exceeds 200 bpm. In addition, it is important to keep in mind that frequency control is the treatment option for fetuses in which reversal to sinus rhythm has not been successful and pulmonary immaturity is present.

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来源期刊
Translational pediatrics
Translational pediatrics Medicine-Pediatrics, Perinatology and Child Health
CiteScore
4.50
自引率
5.00%
发文量
108
期刊介绍: Information not localized
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