持续心脏康复对心力衰竭患者心理和生理预后影响的回顾性研究

IF 2.8 3区 医学 Q1 Pharmacology, Toxicology and Pharmaceutics
Therapeutics and Clinical Risk Management Pub Date : 2025-08-08 eCollection Date: 2025-01-01 DOI:10.2147/TCRM.S529282
Li-Hua Yan, Yun Ge, Fei Wang, Yu-Ling Zhu, Li Lu
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引用次数: 0

摘要

目的:本研究旨在评估持续心脏康复对心力衰竭和改善射血分数(HFimpEF)患者心功能、心理健康和预后的影响。方法:本研究采用回顾性设计,纳入首次急性心肌梗死后射血分数降低的HFimpEF患者150例。所有患者均行急诊经皮冠状动脉介入治疗(PCI)。根据参与心脏康复的情况,将参与者分为对照组(n = 70)和观察组(n = 80)。随访期延长了一年。通过比较分析来评估两组在基线特征、心功能、焦虑和抑郁评分以及心血管事件发生率方面的差异。结果:两组在性别、年龄、既往病史、血脂水平、血糖水平、肾功能等方面均无统计学差异。同样,治疗前心功能评估、6分钟步行测试结果、焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分或心血管事件发生率均无显著差异。与对照组相比,观察组心功能和6分钟步行测试表现明显改善,SAS和SDS评分明显降低。观察组患者心力衰竭和再住院的发生率明显低于对照组。结论:HFimpEF患者的持续心脏康复与心功能的显著改善、6分钟步行测试表现的增强、焦虑和抑郁水平的降低、心力衰竭和再住院的发生率降低相关。这些发现强调了持续心脏康复在改善HFimpEF患者临床结果中的关键作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Impact of Continuous Cardiac Rehabilitation on the Psychological and Physiological Prognosis of Patients with Heart Failure-A Retrospective Study.

Objective: This study aimed to assess the impact of continued cardiac rehabilitation on cardiac function, psychological well-being, and prognostic outcomes in patients diagnosed with heart failure and improved ejection fraction (HFimpEF).

Methods: This study adopted a retrospective design, and a total of 150 patients with HFimpEF who experienced reduced ejection fraction after the first acute myocardial infarction were included. All patients underwent emergency percutaneous coronary intervention (PCI). Participants were categorized into a control group (n = 70) or an observation group (n = 80) based on their participation in ongoing cardiac rehabilitation. The follow-up period extended for one year. Comparative analyses were conducted to assess differences between the two groups in baseline characteristics, cardiac function, anxiety and depression scores, and the incidence of cardiovascular events.

Results: No statistically significant differences were observed between the groups in terms of sex, age, past medical history, blood lipid levels, blood glucose levels, or renal function. Similarly, pre-treatment assessments of cardiac function, six-minute walk test results, Self-Rating Anxiety Scale (SAS) scores, Self-Rating Depression Scale (SDS) scores, or the incidence of cardiovascular events showed no significant differences. Compared to the control group, the observation group demonstrated significantly better cardiac function and six-minute walk test performance, along with significantly lower SAS and SDS scores. Furthermore, the incidence of heart failure and rehospitalization was significantly lower in the observation group than in the control group.

Conclusion: Sustained cardiac rehabilitation in patients with HFimpEF was associated with significant improvements in cardiac function, enhanced six-minute walk test performance, reduced anxiety and depression levels, and a lower incidence of heart failure and rehospitalization. These findings highlight the key role of sustained cardiac rehabilitation in improving clinical outcomes for patients with HFimpEF.

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来源期刊
Therapeutics and Clinical Risk Management
Therapeutics and Clinical Risk Management HEALTH CARE SCIENCES & SERVICES-
CiteScore
5.30
自引率
3.60%
发文量
139
审稿时长
16 weeks
期刊介绍: Therapeutics and Clinical Risk Management is an international, peer-reviewed journal of clinical therapeutics and risk management, focusing on concise rapid reporting of clinical studies in all therapeutic areas, outcomes, safety, and programs for the effective, safe, and sustained use of medicines, therapeutic and surgical interventions in all clinical areas. The journal welcomes submissions covering original research, clinical and epidemiological studies, reviews, guidelines, expert opinion and commentary. The journal will consider case reports but only if they make a valuable and original contribution to the literature. As of 18th March 2019, Therapeutics and Clinical Risk Management will no longer consider meta-analyses for publication. The journal does not accept study protocols, animal-based or cell line-based studies.
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