Madhuri Singh, Mangesh Londhe, Charusheela R Gore, K K Aravinthraj, Akshi Raj
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The Chameleon Tumor: Navigating the Diagnostic Pitfalls of Spindle Squamous Cell Carcinoma.
Spindle cell squamous cell carcinoma (SCSCC) is a rare and aggressive variant of squamous cell carcinoma (SCC). It accounts for 2%-3% of all the SCC and usually arises over sun-exposed areas, prior ionizing radiation sites, or immunocompromised individuals. This uncommon subtype is characterized by the proliferation of both epithelial and mesenchymal components, making diagnosis challenging due to its histopathological resemblance to neoplastic or reactive spindle cell lesions of mesenchymal origin. SCSCC is noteworthy for its high potential for recurrence and early metastasis. immunohistochemistry (IHC) studies play a critical role in differentiating SCSCC from other spindle cell neoplasms, such as spindle cell desmoplastic melanoma, cutaneous leiomyosarcoma, and atypical fibroxanthoma. Herein, we present a rare case report of a 55-year-old male presenting with ulceroproliferative growth on buccal mucosa.
期刊介绍：
The journal Contemporary Clinical Dentistry (CCD) (Print ISSN: 0976-237X, E-ISSN:0976- 2361) is peer-reviewed journal published on behalf of Maharishi Markandeshwar University and issues are published quarterly in the last week of March, June, September and December. The Journal publishes Original research papers, clinical studies, case series strictly of clinical interest. Manuscripts are invited from all specialties of Dentistry i.e. Conservative dentistry and Endodontics, Dentofacial orthopedics and Orthodontics, Oral medicine and Radiology, Oral pathology, Oral surgery, Orodental diseases, Pediatric Dentistry, Periodontics, Clinical aspects of Public Health dentistry and Prosthodontics. Review articles are not accepted. Review, if published, will only be by invitation from eminent scholars and academicians of National and International repute in the field of Medical/Dental education.
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