关于“立体定向消融体放疗（SABR）治疗前列腺癌寡转移灶后PSMA疗效的随访评价”的评论

IF 2.7 3区医学 Q3 ONCOLOGY

Clinical and Translational Radiation Oncology Pub Date : 2025-08-11 DOI:10.1016/j.ctro.2025.101031

Parth Aphale, Himanshu Shekhar, Shashank Dokania

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引用次数: 0

摘要

Zang等人最近发表的研究为基于PSMA-PET/ ct的低转移性前列腺癌（PCa）患者接受立体定向消融体放疗（SABR）的反应评估提供了有价值的见解，显示了令人印象深刻的5年局部控制率为86%，并且在随访间隔[1]期间SUVmax值逐渐降低。虽然这些发现加强了PSMAPET/CT作为局部肿瘤控制的潜在生物标志物的效用，但某些方法学和解释性问题值得深入考虑。

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Comment on “PSMA response evaluation in follow-up PSMA-PET/CT after stereotactic ablative body radiotherapy (SABR) for oligometastases in prostate cancer”

The recently published study by Zang et al. offers valuable insight into PSMA-PET/CTbased response assessment in patients with oligometastatic prostate cancer (PCa) undergoing stereotactic ablative body radiotherapy (SABR), demonstrating an impressive 5-year local control rate of 86 % and progressive reduction in SUVmax values across follow-up intervals [1]. While the findings reinforce the utility of PSMAPET/CT as a potential biomarker for local tumor control, certain methodological and interpretive issues merit deeper consideration.

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