{"title":"40岁女性良性内生纤维瘤:强调早期18F-FES PET/CT应用的重要性。","authors":"Tamer M Dawud, Abdullah T Dawud","doi":"10.1155/crra/9992200","DOIUrl":null,"url":null,"abstract":"<p><p>A 40-year-old female with estrogen receptor-positive breast cancer underwent an initial staging using a technetium-99m methylene diphosphonate (Tc-99m MDP) bone scan, which revealed abnormal uptake in the femur without a patient history of prior trauma or associated symptoms. Subsequently, an MRI confirmed the presence of a well-defined lesion in the upper left femur. To rule out metastatic disease, an 18F-fluoroestradiol (FES) PET/CT was performed, demonstrating no ER expression. Following the PET/CT, a biopsy confirmed the presence of an enchondroma. This case underscores the importance of early utilization of 18F-FES PET/CT in breast cancer staging to minimize unnecessary additional procedures/imaging.</p>","PeriodicalId":30326,"journal":{"name":"Case Reports in Radiology","volume":"2025 ","pages":"9992200"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339146/pdf/","citationCount":"0","resultStr":"{\"title\":\"Benign Enchondroma in a 40-Year-Old Female: Emphasizing the Importance of Early 18F-FES PET/CT Utilization.\",\"authors\":\"Tamer M Dawud, Abdullah T Dawud\",\"doi\":\"10.1155/crra/9992200\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A 40-year-old female with estrogen receptor-positive breast cancer underwent an initial staging using a technetium-99m methylene diphosphonate (Tc-99m MDP) bone scan, which revealed abnormal uptake in the femur without a patient history of prior trauma or associated symptoms. Subsequently, an MRI confirmed the presence of a well-defined lesion in the upper left femur. To rule out metastatic disease, an 18F-fluoroestradiol (FES) PET/CT was performed, demonstrating no ER expression. Following the PET/CT, a biopsy confirmed the presence of an enchondroma. This case underscores the importance of early utilization of 18F-FES PET/CT in breast cancer staging to minimize unnecessary additional procedures/imaging.</p>\",\"PeriodicalId\":30326,\"journal\":{\"name\":\"Case Reports in Radiology\",\"volume\":\"2025 \",\"pages\":\"9992200\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-08-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339146/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Radiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/crra/9992200\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Radiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/crra/9992200","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Benign Enchondroma in a 40-Year-Old Female: Emphasizing the Importance of Early 18F-FES PET/CT Utilization.
A 40-year-old female with estrogen receptor-positive breast cancer underwent an initial staging using a technetium-99m methylene diphosphonate (Tc-99m MDP) bone scan, which revealed abnormal uptake in the femur without a patient history of prior trauma or associated symptoms. Subsequently, an MRI confirmed the presence of a well-defined lesion in the upper left femur. To rule out metastatic disease, an 18F-fluoroestradiol (FES) PET/CT was performed, demonstrating no ER expression. Following the PET/CT, a biopsy confirmed the presence of an enchondroma. This case underscores the importance of early utilization of 18F-FES PET/CT in breast cancer staging to minimize unnecessary additional procedures/imaging.