Devices for non-fragmented removal of thrombus via mechanical grip: a patent review.

Introduction: Thromboembolic conditions are a leading global cause of mortality and a major cause of disability. Throughout the years mechanical thrombectomy has become a preferred method of treatment. Removing thrombus in its entirety on first pass decreases procedure time as well as lowers the risk of distal embolization.

Areas covered: This review provides a comprehensive overview and classification of the patent literature on devices for non-fragmented thrombus removal via grip. Patentscope database was used to search for internationally granted patents published any time before the access date (October 2024). The search using keywords and patent classification code led to identifying 141 relevant patents that were then categorized based on location and type of grip they describe.

Expert opinion: The designs found are analyzed in the discussion and a broader context for their relevance is given in the expert opinion section. The following review can provide insight into possible mechanical thrombectomy methods, general trends in the field as well as serve as an inspiration in development of novel devices.