[急性胆源性胰腺炎胰腺支架置入术的疗效和安全性]。

Q4 Medicine
A I Khripun, A N Alimov, S Yu Orlov, T P Chelyapina, M V Monakhov, A M Olenichev, E E Kudryavitskii
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引用次数: 0

摘要

目的:评价急性胆源性胰腺炎早期胰支架置入术的疗效和安全性。材料和方法:我们回顾性分析早期(入院后48小时内)胰腺支架置入术对重症急性胆源性胰腺炎患者疾病严重程度、并发症发生率、死亡率和住院时间的影响。此外,也有急性胆源性胰腺炎患者接受了延迟内镜逆行干预和仅保守治疗。结果:与延迟干预和保守治疗相比,早期胰腺支架置入术降低了局部并发症(p=0.047)和全身并发症(p=0.027)的风险。与延迟干预相比,早期胰腺支架植入缩短了住院时间(p=0.038)。两组之间在死亡率和疾病严重程度上没有差异。48小时后行胰腺支架置入术与早期支架置入术或保守治疗相比没有优势,但明显增加了感染胰腺坏死的风险(p=0.023)。结论:早期胰支架置入术在减少急性胆源性胰腺炎患者并发症方面是安全有效的。早期和晚期胰腺支架植入对疾病严重程度、死亡率和住院时间都没有显著影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Efficacy and safety of pancreatic stenting in acute biliary pancreatitis].

Objective: To evaluate the efficacy and safety of early pancreatic stenting in patients with acute biliary pancreatitis.

Material and methods: We retrospectively analyzed the effect of early (within 48 hours after admission) pancreatic stenting on severity of disease, incidence of complications, mortality and hospital-stay in patients with severe acute biliary pancreatitis. Moreover, there were patients with acute biliary pancreatitis who underwent delayed endoscopic retrograde intervention and only conservative therapy.

Results: Early pancreatic stenting reduced the risk of local (p=0.047) and systemic complications (p=0.027) compared to delayed intervention and conservative treatment. Early pancreatic stenting contributed to shorter hospital-stay when compared with delayed intervention (p=0.038). There was no between-group difference in mortality or severity of disease. Pancreatic stenting after 48 hours had no advantages over early stenting or conservative treatment, but significantly increased the risk of infected pancreatic necrosis (p=0.023).

Conclusion: Early pancreatic stenting seems to be safe and effective procedure in reducing the number of complications in patients with acute biliary pancreatitis. Neither early nor late pancreatic stenting has a significant effect on disease severity, mortality and hospital-stay.

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来源期刊
Khirurgiya
Khirurgiya Medicine-Medicine (all)
CiteScore
0.70
自引率
0.00%
发文量
161
期刊介绍: Хирургия отдельных областей сердце, сосуды легкие пищевод молочная железа желудок и двенадцатиперстная кишка кишечник желчевыводящие пути печень
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