{"title":"青少年的暂时性构音障碍和偏瘫。","authors":"Yasutaka Yanagita, Kiyoshi Shikino","doi":"10.12890/2025_005597","DOIUrl":null,"url":null,"abstract":"<p><p>An adolescent male in his teens had recurrent episodes of transient left lower limb weakness, persisting for three years. These episodes were consistently triggered by specific movements, such as postural changes or movement initiation, occurring multiple times per day. The patient adapted his behaviour to avoid triggering symptoms. Based on the clinical presentation, paroxysmal kinesigenic dyskinesia was diagnosed. Although dysarthria is uncommon in paroxysmal kinesigenic dyskinesia, its presence in this case highlights the condition's clinical variability. Carbamazepine therapy was initiated, which resulted in a significant reduction in the frequency of episodes. This case underscores the importance of recognising movement-triggered transient motor symptoms, including rare symptoms such as dysarthria, to prevent misdiagnosis and unnecessary testing. Early recognition and treatment can significantly improve outcomes and quality of life in patients with paroxysmal kinesigenic dyskinesia.</p><p><strong>Learning points: </strong>Paroxysmal kinesigenic dyskinesia is a rare disorder characterised by brief, recurrent episodes of involuntary movements triggered by sudden voluntary motion.Atypical symptoms such as dysarthria and hemiparesis in paroxysmal kinesigenic dyskinesia may mimic transient ischaemic attacks or structural brain lesions.Anticonvulsants such as carbamazepine are highly effective in treating paroxysmal kinesigenic dyskinesia and can significantly reduce episode frequency and improve quality of life when initiated early.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 8","pages":"005597"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12331277/pdf/","citationCount":"0","resultStr":"{\"title\":\"Transient Dysarthria and Hemiparesis in an Adolescent.\",\"authors\":\"Yasutaka Yanagita, Kiyoshi Shikino\",\"doi\":\"10.12890/2025_005597\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>An adolescent male in his teens had recurrent episodes of transient left lower limb weakness, persisting for three years. These episodes were consistently triggered by specific movements, such as postural changes or movement initiation, occurring multiple times per day. The patient adapted his behaviour to avoid triggering symptoms. Based on the clinical presentation, paroxysmal kinesigenic dyskinesia was diagnosed. Although dysarthria is uncommon in paroxysmal kinesigenic dyskinesia, its presence in this case highlights the condition's clinical variability. Carbamazepine therapy was initiated, which resulted in a significant reduction in the frequency of episodes. This case underscores the importance of recognising movement-triggered transient motor symptoms, including rare symptoms such as dysarthria, to prevent misdiagnosis and unnecessary testing. Early recognition and treatment can significantly improve outcomes and quality of life in patients with paroxysmal kinesigenic dyskinesia.</p><p><strong>Learning points: </strong>Paroxysmal kinesigenic dyskinesia is a rare disorder characterised by brief, recurrent episodes of involuntary movements triggered by sudden voluntary motion.Atypical symptoms such as dysarthria and hemiparesis in paroxysmal kinesigenic dyskinesia may mimic transient ischaemic attacks or structural brain lesions.Anticonvulsants such as carbamazepine are highly effective in treating paroxysmal kinesigenic dyskinesia and can significantly reduce episode frequency and improve quality of life when initiated early.</p>\",\"PeriodicalId\":11908,\"journal\":{\"name\":\"European journal of case reports in internal medicine\",\"volume\":\"12 8\",\"pages\":\"005597\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12331277/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European journal of case reports in internal medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.12890/2025_005597\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European journal of case reports in internal medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12890/2025_005597","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Transient Dysarthria and Hemiparesis in an Adolescent.
An adolescent male in his teens had recurrent episodes of transient left lower limb weakness, persisting for three years. These episodes were consistently triggered by specific movements, such as postural changes or movement initiation, occurring multiple times per day. The patient adapted his behaviour to avoid triggering symptoms. Based on the clinical presentation, paroxysmal kinesigenic dyskinesia was diagnosed. Although dysarthria is uncommon in paroxysmal kinesigenic dyskinesia, its presence in this case highlights the condition's clinical variability. Carbamazepine therapy was initiated, which resulted in a significant reduction in the frequency of episodes. This case underscores the importance of recognising movement-triggered transient motor symptoms, including rare symptoms such as dysarthria, to prevent misdiagnosis and unnecessary testing. Early recognition and treatment can significantly improve outcomes and quality of life in patients with paroxysmal kinesigenic dyskinesia.
Learning points: Paroxysmal kinesigenic dyskinesia is a rare disorder characterised by brief, recurrent episodes of involuntary movements triggered by sudden voluntary motion.Atypical symptoms such as dysarthria and hemiparesis in paroxysmal kinesigenic dyskinesia may mimic transient ischaemic attacks or structural brain lesions.Anticonvulsants such as carbamazepine are highly effective in treating paroxysmal kinesigenic dyskinesia and can significantly reduce episode frequency and improve quality of life when initiated early.
期刊介绍:
The European Journal of Case Reports in Internal Medicine is an official journal of the European Federation of Internal Medicine (EFIM), representing 35 national societies from 33 European countries. The Journal''s mission is to promote the best medical practice and innovation in the field of acute and general medicine. It also provides a forum for internal medicine doctors where they can share new approaches with the aim of improving diagnostic and clinical skills in this field. EJCRIM welcomes high-quality case reports describing unusual or complex cases that an internist may encounter in everyday practice. The cases should either demonstrate the appropriateness of a diagnostic/therapeutic approach, describe a new procedure or maneuver, or show unusual manifestations of a disease or unexpected reactions. The Journal only accepts and publishes those case reports whose learning points provide new insight and/or contribute to advancing medical knowledge both in terms of diagnostics and therapeutic approaches. Case reports of medical errors, therefore, are also welcome as long as they provide innovative measures on how to prevent them in the current practice (Instructive Errors). The Journal may also consider brief and reasoned reports on issues relevant to the practice of Internal Medicine, as well as Abstracts submitted to the scientific meetings of acknowledged medical societies.