Analysis of Saposhnikoviae Radix and Libonotidis Radix Based on “Characteristic Ion Set” and Chemometrics

To enrich detection methods of Saposhnikoviae Radix (SR) adulterated Libonotidis Radix (LR) and improve the screening efficiency, this paper conducted an analysis of SR and LR based on chemometrics and “characteristic ion set.” Firstly, the samples were analyzed by liquid chromatography-mass spectrometer and converted into data matrix. After feature algorithm extraction, the “characteristic ion set” of SR and LR was obtained to match the test and blind market samples for feedback matching index (MI). In addition, the LR proprietary component was extracted to verify the MI analysis based on “characteristic ion set.” Three percent LR adulteration was identified based on “characteristic ion set,” and two market blind samples were identified as adulterated samples. Xanthalin was the LR proprietary component. Moreover, the analysis based on “characteristic ion set” is reliable through chemometric analysis and extraction of proprietary ions. “Characteristic ion set” and chemometrics can enrich the detection methods of SR and LR and improve the screening efficiency.