在长期氧疗中,较长的每日氧用量与更多的不良事件、症状和较差的健康状况相关。

IF 2.3 3区 医学 Q2 RESPIRATORY SYSTEM
Chronic Respiratory Disease Pub Date : 2025-01-01 Epub Date: 2025-08-08 DOI:10.1177/14799731251366962
Filip Björklund, Magnus Ekström
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引用次数: 0

摘要

每天使用超过15小时的长期氧疗(LTOT)不能降低死亡率或住院率,但可能增加不良事件的风险。我们评估了每日供氧时间与LTOT患者的不良事件、症状和健康状况之间的关系。方法:这是一项横断面调查研究,随机抽样(N = 650)瑞典正在进行LTOT的成年人。报告氧气使用(h/day),并分析其与不良事件、症状严重程度(修订后的埃德蒙顿症状评估系统)、睡眠时间和质量以及健康状况(COPD评估试验[CAT])的关联。结果共分析了204例患者的调查结果;60%为女性,平均年龄75.3岁(SD 8.7)。抽样调查对象和非调查对象的Swedevox基线特征相似。与报告较少氧气使用时间的患者相比,报告24小时每日氧气使用的患者(53.4%)也报告了更高的总不良事件数量,更高的呼吸困难,抑郁和焦虑评分,以及更差的健康状况。在粗糙和调整后的线性回归模型中,较长的每日供氧时间也与较高的不良事件发生率、较高的呼吸困难和焦虑评分以及较差的健康状况评分相关。氧气使用时间与睡眠质量或持续时间之间没有关联。结论每日供氧时间越长,不良事件越多,部分症状严重程度越高,健康状况越差。需要进一步的研究来确定因果关系的证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Longer daily oxygen use associates with more adverse events, symptoms, and worse health status in long-term oxygen therapy.

Longer daily oxygen use associates with more adverse events, symptoms, and worse health status in long-term oxygen therapy.

Longer daily oxygen use associates with more adverse events, symptoms, and worse health status in long-term oxygen therapy.

Longer daily oxygen use associates with more adverse events, symptoms, and worse health status in long-term oxygen therapy.

IntroductionUse of long-term oxygen therapy (LTOT) for more than 15 h per day does not reduce mortality or hospitalizations, but may increase the risk of adverse events. We evaluated the relationship between daily oxygen use duration and adverse events, symptoms, and health status in patients on LTOT.MethodsThis was a cross-sectional survey study of a random sample (N = 650) of adults with ongoing LTOT in Sweden. Oxygen use (h/day) was reported, and associations were analyzed with adverse events, symptom severities (revised Edmonton Symptom Assessment System), sleep duration and quality, and health status (COPD assessment test [CAT]).ResultsIn total, surveys from 204 patients were analyzed; 60% female, mean age 75.3 (SD 8.7) years. Swedevox baseline characteristics were similar between sampled respondents and non-respondents. Patients reporting 24 h of daily oxygen use (53.4%) also reported a higher number of total adverse events, higher ratings of dyspnea, depression and anxiety, and worse health status, compared to those reporting fewer hours of oxygen use. A longer daily duration of oxygen use also associated with a higher number of experienced adverse events, higher ratings of dyspnea and anxiety, and worse rated health status in crude and adjusted linear regression models. No associations were seen between oxygen use duration and sleep quality or duration.ConclusionMore adverse events, a higher severity of some symptoms, and worse health status are seen among patients with a longer daily duration of oxygen use. Further research is needed to establish evidence of causality.

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来源期刊
Chronic Respiratory Disease
Chronic Respiratory Disease RESPIRATORY SYSTEM-
CiteScore
5.90
自引率
7.30%
发文量
47
审稿时长
11 weeks
期刊介绍: Chronic Respiratory Disease is a peer-reviewed, open access, scholarly journal, created in response to the rising incidence of chronic respiratory diseases worldwide. It publishes high quality research papers and original articles that have immediate relevance to clinical practice and its multi-disciplinary perspective reflects the nature of modern treatment. The journal provides a high quality, multi-disciplinary focus for the publication of original papers, reviews and commentary in the broad area of chronic respiratory disease, particularly its treatment and management.
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