{"title":"确定冠状动脉疾病严重程度的新标志物：代谢冠状动脉危险指数。","authors":"Yücel Kanal, Idris Yakut","doi":"10.5830/CVJA-2025-011","DOIUrl":null,"url":null,"abstract":"<p><p>Despite advances in prevention and treatment, coronary artery disease (CAD) remains a major cause of death globally. Glycated haemoglobin (HbA1c) and body mass index (BMI) are known risk factors for CAD. This study aimed to investigate the relationship between the metabolic coronary risk index (MCRI) and the severity of CAD, measured by the SYNTAX score (SS), in patients with acute coronary syndrome (ACS) who underwent coronary angiography (CAG). A total of 214 patients were included, with a mean age of 59.29 ± 11.93 years, and 25.7% were female. Regression analysis showed that MCRI independently predicted CAD severity. MCRI differentiated moderate and high SS from low SS with 70% sensitivity and 50% specificity at a cutoff value of 158.9. The study concluded that MCRI is a significant predictor of CAD severity in ACS patients.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"36 2","pages":"129-133"},"PeriodicalIF":0.7000,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A novel marker for determining the severity of coronary artery disease: the metabolic coronary risk index.\",\"authors\":\"Yücel Kanal, Idris Yakut\",\"doi\":\"10.5830/CVJA-2025-011\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Despite advances in prevention and treatment, coronary artery disease (CAD) remains a major cause of death globally. Glycated haemoglobin (HbA1c) and body mass index (BMI) are known risk factors for CAD. This study aimed to investigate the relationship between the metabolic coronary risk index (MCRI) and the severity of CAD, measured by the SYNTAX score (SS), in patients with acute coronary syndrome (ACS) who underwent coronary angiography (CAG). A total of 214 patients were included, with a mean age of 59.29 ± 11.93 years, and 25.7% were female. Regression analysis showed that MCRI independently predicted CAD severity. MCRI differentiated moderate and high SS from low SS with 70% sensitivity and 50% specificity at a cutoff value of 158.9. The study concluded that MCRI is a significant predictor of CAD severity in ACS patients.</p>\",\"PeriodicalId\":9434,\"journal\":{\"name\":\"Cardiovascular Journal of Africa\",\"volume\":\"36 2\",\"pages\":\"129-133\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cardiovascular Journal of Africa\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.5830/CVJA-2025-011\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/6/20 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cardiovascular Journal of Africa","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5830/CVJA-2025-011","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/20 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
A novel marker for determining the severity of coronary artery disease: the metabolic coronary risk index.
Despite advances in prevention and treatment, coronary artery disease (CAD) remains a major cause of death globally. Glycated haemoglobin (HbA1c) and body mass index (BMI) are known risk factors for CAD. This study aimed to investigate the relationship between the metabolic coronary risk index (MCRI) and the severity of CAD, measured by the SYNTAX score (SS), in patients with acute coronary syndrome (ACS) who underwent coronary angiography (CAG). A total of 214 patients were included, with a mean age of 59.29 ± 11.93 years, and 25.7% were female. Regression analysis showed that MCRI independently predicted CAD severity. MCRI differentiated moderate and high SS from low SS with 70% sensitivity and 50% specificity at a cutoff value of 158.9. The study concluded that MCRI is a significant predictor of CAD severity in ACS patients.
期刊介绍：
The Cardiovascular Journal of Africa (CVJA) is an international peer-reviewed journal that keeps cardiologists up to date with advances in the diagnosis and treatment of cardiovascular disease. Topics covered include coronary disease, electrophysiology, valve disease, imaging techniques, congenital heart disease (fetal, paediatric and adult), heart failure, surgery, and basic science.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
