Engin Algül, Nail Burak Özbeyaz, Haluk Furkan Şahan, Faruk Aydınyılmaz, Hamza Sunman, Tolga Han Efe, Özcan Özdemir
{"title":"血小板与血红蛋白比值预测左室血栓的发展。","authors":"Engin Algül, Nail Burak Özbeyaz, Haluk Furkan Şahan, Faruk Aydınyılmaz, Hamza Sunman, Tolga Han Efe, Özcan Özdemir","doi":"10.5830/CVJA-2025-021","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Apical thrombus (AT) is a severe complication in myocardial infarction (MI), increasing the risk of thromboembolic events. Platelet-to-haemoglobin ratio (PHR) is a novel, inexpensive predictor of cardiovascular outcomes. This study explores the association between PHR and AT in MI patients.</p><p><strong>Materials & methods: </strong>This retrospective study included 690 anterior MI patients (314 patients with AT and 376 patients without AT as a control group). Blood samples were analysed to calculate PHR, and echocardiographic evaluations identified AT. Logistic regression and ROC analysis determined independent predictors and the optimal PHR cut-off value for AT.</p><p><strong>Results: </strong>PHRwas significantly higher in the AT group (2.03 ± 0.64 vs. 1.85 ± 0.50; <i>p</i> <0.001).Multivariate analysis identified PHR, proximal LAD lesions, and lower LVEF as independent predictors. The PHR cut-off of 1.88 showed 69.3% sensitivity and 68.4% specificity.</p><p><strong>Conclusion: </strong>PHR is a simple, accessible marker for predicting AT in MI patients. Its use may improve early risk stratification and clinical outcomes.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"36 2","pages":"191-195"},"PeriodicalIF":0.7000,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Platelet-to-Haemoglobin Ratio Predicts the Development of Left Ventricular Apical Thrombus.\",\"authors\":\"Engin Algül, Nail Burak Özbeyaz, Haluk Furkan Şahan, Faruk Aydınyılmaz, Hamza Sunman, Tolga Han Efe, Özcan Özdemir\",\"doi\":\"10.5830/CVJA-2025-021\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Apical thrombus (AT) is a severe complication in myocardial infarction (MI), increasing the risk of thromboembolic events. Platelet-to-haemoglobin ratio (PHR) is a novel, inexpensive predictor of cardiovascular outcomes. This study explores the association between PHR and AT in MI patients.</p><p><strong>Materials & methods: </strong>This retrospective study included 690 anterior MI patients (314 patients with AT and 376 patients without AT as a control group). Blood samples were analysed to calculate PHR, and echocardiographic evaluations identified AT. Logistic regression and ROC analysis determined independent predictors and the optimal PHR cut-off value for AT.</p><p><strong>Results: </strong>PHRwas significantly higher in the AT group (2.03 ± 0.64 vs. 1.85 ± 0.50; <i>p</i> <0.001).Multivariate analysis identified PHR, proximal LAD lesions, and lower LVEF as independent predictors. The PHR cut-off of 1.88 showed 69.3% sensitivity and 68.4% specificity.</p><p><strong>Conclusion: </strong>PHR is a simple, accessible marker for predicting AT in MI patients. Its use may improve early risk stratification and clinical outcomes.</p>\",\"PeriodicalId\":9434,\"journal\":{\"name\":\"Cardiovascular Journal of Africa\",\"volume\":\"36 2\",\"pages\":\"191-195\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cardiovascular Journal of Africa\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.5830/CVJA-2025-021\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cardiovascular Journal of Africa","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5830/CVJA-2025-021","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Platelet-to-Haemoglobin Ratio Predicts the Development of Left Ventricular Apical Thrombus.
Objective: Apical thrombus (AT) is a severe complication in myocardial infarction (MI), increasing the risk of thromboembolic events. Platelet-to-haemoglobin ratio (PHR) is a novel, inexpensive predictor of cardiovascular outcomes. This study explores the association between PHR and AT in MI patients.
Materials & methods: This retrospective study included 690 anterior MI patients (314 patients with AT and 376 patients without AT as a control group). Blood samples were analysed to calculate PHR, and echocardiographic evaluations identified AT. Logistic regression and ROC analysis determined independent predictors and the optimal PHR cut-off value for AT.
Results: PHRwas significantly higher in the AT group (2.03 ± 0.64 vs. 1.85 ± 0.50; p <0.001).Multivariate analysis identified PHR, proximal LAD lesions, and lower LVEF as independent predictors. The PHR cut-off of 1.88 showed 69.3% sensitivity and 68.4% specificity.
Conclusion: PHR is a simple, accessible marker for predicting AT in MI patients. Its use may improve early risk stratification and clinical outcomes.
期刊介绍：
The Cardiovascular Journal of Africa (CVJA) is an international peer-reviewed journal that keeps cardiologists up to date with advances in the diagnosis and treatment of cardiovascular disease. Topics covered include coronary disease, electrophysiology, valve disease, imaging techniques, congenital heart disease (fetal, paediatric and adult), heart failure, surgery, and basic science.
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