对局：液体活检晋级下一轮。

IF 10.2 1区医学 Q1 ONCOLOGY

Clinical Cancer Research Pub Date : 2025-08-08 DOI:10.1158/1078-0432.ccr-25-1927

Alessandro Russo,Paola Muscolino,Christian Rolfo

引用次数: 0

摘要

最近的一篇文章评估了肿瘤和血浆基因分型之间的一致性率，用于检测可操作的基因组改变，以指导靶向治疗。这些结果支持液体活检在招募患者进入基因组引导试验中的效用，特别是在无法获得组织或活检不可行的情况下。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Game-set-MATCH: Liquid biopsy advances to the next round.

A recent article evaluated the concordance rate between tumor and plasma genotyping for detecting actionable genomic alterations to guide targeted therapy. These results support the utility of liquid biopsy for enrolling patients into genomically-guided trials, especially in scenarios where tissue is unavailable or biopsy is not feasible.

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来源期刊

Clinical Cancer Research 医学-肿瘤学

CiteScore

20.10

自引率

1.70%

发文量

1207

审稿时长

2.1 months

期刊介绍： Clinical Cancer Research is a journal focusing on groundbreaking research in cancer, specifically in the areas where the laboratory and the clinic intersect. Our primary interest lies in clinical trials that investigate novel treatments, accompanied by research on pharmacology, molecular alterations, and biomarkers that can predict response or resistance to these treatments. Furthermore, we prioritize laboratory and animal studies that explore new drugs and targeted agents with the potential to advance to clinical trials. We also encourage research on targetable mechanisms of cancer development, progression, and metastasis.