对乍得东部苏丹难民营实施EWARS流动流行病学监测工具的评价:一项基于人群的回顾性监测研究。

Frontiers in epidemiology Pub Date : 2025-07-23 eCollection Date: 2025-01-01 DOI:10.3389/fepid.2025.1604446
Stephane Tewo, Balde Thierno, Freddy M Banza, Idriss M Mahamat, N'dri K Eric-Didier, Djinguebey N Raoul, John Otokoye Otshudiema, Castilla Echenique Jorge, Moussa Brahimi, Djoumbarina Maina, Evers Egmond, Marcel Woung, Kazuki Shimizu, Boris I Pavlin, Jacques L Tamuzi, Patrick D M C Katoto, Charles S Wiysonge, Blanche-Philomene Melanga Anya
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引用次数: 0

摘要

背景:苏丹冲突的升级给邻国,特别是乍得东部地区带来了重大的人道主义挑战。这种人道主义环境的卫生需求是独特的,因为它们更容易受到容易爆发的疾病和缺乏基本服务的影响。为了应对这些挑战,世界卫生组织支持实施早期预警和反应系统(EWARS)移动。本研究的目的是评估EWARS流动流行病学监测工具在乍得东部苏丹儿童难民中的应用情况。方法:这是一项基于人群的回顾性监测研究,概述了与潜在疫情有关的时间和空间上的病例和死亡模式。结果:在Quaddai、Sila和Wadi Fira等脆弱省份的儿童中,总共报告了1,645起警报。有41738例警报病例和236例死亡,预计死亡率为0.56%。EWARS移动成功报告了急性弛缓性麻痹(AFP)、急性黄疸综合征(AJS)、急性呼吸道感染(ARI)、儿童急性水样腹泻(AWD)、麻疹、脑膜炎、白喉、新生儿破伤风(NT)、登革热、痢疾和易感儿童非典型事件在时间和空间上的急剧增加。各级(营、区、区、省)成功完成病例报告、警报记录和周报告(完成率≥80%)。相比之下,警报报告、每周报告和可能爆发的及时性在各个级别上表现不佳(及时性率≥80%)。流行曲线显示了多种可能的暴发类型,其特征为点源(5岁以下的AJS和AWD)、普通源(5岁及以上的AWD)、传播源(ARI和痢疾)和间歇源(AFP、麻疹、脑膜炎、白喉、NT和异常事件)。敏感性为81%(79% ~ 83%),阳性预测值为72.0%(68% ~ 75%)。结论:在这场严重的人道主义危机中,EWARS流动项目是乍得东部各省在疫情前和疫情爆发期间对弱势儿童实施的一项切实可行的解决方案。但是,应努力改进所有国家以下各级的及时性指标,并纳入警报指标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Evaluation of the implementation of the EWARS Mobile epidemiological surveillance tool in Sudanese refugee camps in Eastern Chad: a retrospective and population-based surveillance study.

Evaluation of the implementation of the EWARS Mobile epidemiological surveillance tool in Sudanese refugee camps in Eastern Chad: a retrospective and population-based surveillance study.

Evaluation of the implementation of the EWARS Mobile epidemiological surveillance tool in Sudanese refugee camps in Eastern Chad: a retrospective and population-based surveillance study.

Evaluation of the implementation of the EWARS Mobile epidemiological surveillance tool in Sudanese refugee camps in Eastern Chad: a retrospective and population-based surveillance study.

Background: The escalation of the conflict in Sudan has created a major humanitarian challenge for neighboring countries, especially in the Eastern regions of Chad. This humanitarian setting's health needs are unique in that they are more vulnerable to both outbreak-prone disease and a lack of essential services. To address these challenges, the World Health Organization has supported implementing the Early Warning Alert and Response System (EWARS) Mobile. The purpose of this study was to evaluate the application of the EWARS Mobile epidemiological surveillance tool in Sudanese children's refugees in Eastern Chad.

Methods: This was a retrospective and population-based surveillance study that provided an overview of the pattern of cases and deaths in time and space related to potential outbreaks.

Results: In total, 1,645 alerts were reported among children in vulnerable provinces of Quaddai, Sila, and Wadi Fira. There were 41,738 alerted cases and 236 deaths, for a 0.56% projected fatality rate. The EWARS Mobile successfully reported alerted increases in cases of acute flaccid paralysis (AFP), acute jaundice syndrome (AJS), acute respiratory infection (ARI), acute watery diarrhea in children (AWD), measles, meningitis, diphtheria, neonatal tetanus (NT), dengue, dysentery, and atypical events in vulnerable children in time and space. Case reporting, alert recording, and weekly reporting were completed successfully at all levels (camps, district, zone, and province) (≥80% completion rate). In contrast, the timeliness of alert reporting, weekly reporting, and probable outbreaks did not perform well across levels (≥80% timeliness rate). Epidemic curves indicated multiple probable outbreak types, characterized by a point source (AJS and AWD under 5 years), common source (AWD in 5 years and above), propagated source (ARI and dysentery), and intermittent source (AFP, measles, meningitis, diphtheria, NT, and unusual events). The sensitivity and positive predictive value were estimated at 81% (79%-83%) and 72.0% (68%-75%), respectively.

Conclusions: The EWARS Mobile is a practical solution for Eastern Chad provinces to implement throughout the pre-epidemic and outbreak periods in vulnerable children in this severe humanitarian crisis. However, efforts should be made to improve timeliness indicators at all subnational levels and incorporate alarm indicators.

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