实验室全面自动化:符合预期目的?

IF 3.7 2区 医学 Q1 MEDICAL LABORATORY TECHNOLOGY
Mario Plebani
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引用次数: 0

摘要

自20世纪80年代以来,自动化深刻地改变了临床实验室的操作,提高了效率、标准化和吞吐量。这种技术的发展使实验室能够满足不断增长的测试需求,解决持续的劳动力短缺问题,并控制操作成本。除了分析巩固之外,通过分析前和分析后阶段的整合取得了重大进展,从而提高了总测试过程(TTP)的整体质量。尽管全面实验室自动化(TLA)的好处得到了广泛认可——特别是提高了工作人员的安全性和更快的周转时间——但也出现了一些限制,特别是在操作挑战和缺乏临床有效性证据方面。未来的改进应集中在前-前分析流程的整合、检测平台的小型化、所有检验医学亚专业的整合以及加强数据管理。然而,最关键的问题仍然是有限的证据支持TLA对关键临床结果的影响,如缩短急诊科和医院病房的住院时间,优化诊断-治疗途径,提高护理质量,降低发病率和死亡率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Total laboratory automation: fit for its intended purposes?

Since the 1980s, automation has profoundly transformed clinical laboratory operations, enhancing efficiency, standardization, and throughput. This technological evolution has enabled laboratories to meet rising testing demands, address persistent workforce shortages, and control operational costs. Beyond analytical consolidation, significant progress has been made through the integration of pre-analytical and post-analytical phases, thereby improving the overall quality of the Total Testing Process (TTP). Despite the well-recognized benefits of Total Laboratory Automation (TLA) - notably improved worker safety and faster turnaround times - a number of limitations have emerged, particularly concerning operational challenges and the lack of evidence for clinical effectiveness. Future improvements should focus on the integration of pre-pre-analytical processes, miniaturization of testing platforms, consolidation of all laboratory medicine subspecialties, and enhanced data management. However, the most critical issue remains the limited evidence supporting the impact of TLA on key clinical outcomes - such as reduced length of stay in emergency departments and hospital wards, optimized diagnostic-therapeutic pathways, improved quality of care, and reduced morbidity and mortality.

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来源期刊
Clinical chemistry and laboratory medicine
Clinical chemistry and laboratory medicine 医学-医学实验技术
CiteScore
11.30
自引率
16.20%
发文量
306
审稿时长
3 months
期刊介绍: Clinical Chemistry and Laboratory Medicine (CCLM) publishes articles on novel teaching and training methods applicable to laboratory medicine. CCLM welcomes contributions on the progress in fundamental and applied research and cutting-edge clinical laboratory medicine. It is one of the leading journals in the field, with an impact factor over 3. CCLM is issued monthly, and it is published in print and electronically. CCLM is the official journal of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) and publishes regularly EFLM recommendations and news. CCLM is the official journal of the National Societies from Austria (ÖGLMKC); Belgium (RBSLM); Germany (DGKL); Hungary (MLDT); Ireland (ACBI); Italy (SIBioC); Portugal (SPML); and Slovenia (SZKK); and it is affiliated to AACB (Australia) and SFBC (France). Topics: - clinical biochemistry - clinical genomics and molecular biology - clinical haematology and coagulation - clinical immunology and autoimmunity - clinical microbiology - drug monitoring and analysis - evaluation of diagnostic biomarkers - disease-oriented topics (cardiovascular disease, cancer diagnostics, diabetes) - new reagents, instrumentation and technologies - new methodologies - reference materials and methods - reference values and decision limits - quality and safety in laboratory medicine - translational laboratory medicine - clinical metrology Follow @cclm_degruyter on Twitter!
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