临床实践和卫生政策的重要更新

IF 8.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Aajuli Shukla
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引用次数: 0

摘要

这一期的MJA有几篇文章,提供了新的指导方针和见解,对重要的临床条件的管理和后果。关于妊娠期糖尿病管理的最新指南现已出版澳大利亚妊娠糖尿病协会(ADIPS)的2025年共识建议基于现有证据和利益相关者咨询,更新了妊娠期高血糖筛查、诊断和分类指南Sweeting及其同事提出的这些共识建议很重要;这些更新的建议提高了妊娠期糖尿病的诊断血糖阈值,并明确了妊娠期有高血糖危险因素的妇女的妊娠早期筛查方法。现在建议在妊娠早期产前血液检查时检测糖化血红蛋白,以帮助医生进行风险分层。对于高危妇女早期口服葡萄糖耐量试验需要考虑的事项也有指导。随着妊娠糖尿病发病率的持续上升,这种疾病的诊断和管理可能是大多数全科医生的执业范围,特别是在难以获得专家团队的区域和偏远地区。这些建议对医疗从业者来说是一个受欢迎的更新。Zhang和他的同事在一篇文章中以糖尿病为特征,他们检查了糖尿病足部服务中心的信息,并将其与昆士兰医院入院患者数据联系起来,以评估糖尿病相关足部溃疡(DFU)患者的发病率、风险因素和住院时间,包括截肢和不截肢随着糖尿病及其相关并发症发病率的增加,这种情况在人群中也越来越普遍。DFU患者中与DFU相关的住院发生率很高,尽管大多数不涉及截肢。深溃疡或严重外周动脉疾病患者发生dfu相关住院的风险更高。作者认为,这些发现可以帮助服务部门确定哪些DFU患者将从强化干预中获益最多,从而有可能避免大量与糖尿病相关的住院治疗。在本期的另一篇临床重点文章中,Seeley和他的同事分析了澳大利亚体位性心动过速综合征(POTS)患者登记的数据,以评估南澳大利亚POTS患者的症状负担、生活质量和诊断历史。这是澳大利亚第一个基于医生确诊的POTS患者登记数据的研究。主要发现是,尽管看过几位医生,但症状出现和诊断之间的时间间隔很长,社会参与减少,失业率高,相对年轻的POTS患者生活质量低。本研究的平均诊断延迟时间比国外报道的要长,这表明澳大利亚医疗保健存在独特的障碍。这在未来将变得更加重要,因为感染SARS-CoV-2是报告中最常见的引发病情发展的因素。一篇文章总结了澳大利亚信息专员办公室(OAIC)最近更新的指导意见,明确了临床医生在不违反联邦隐私法的情况下协助患者通知其亲属遗传风险的自由裁量权,为支持遗传疾病患者的医生提供了重要建议。Tiller和Otlowski研究了临床医生在这种情况下的作用作者从病人、他们的亲属和临床医生在管理期望方面的角色的角度讨论了这一挑战,这两方面都是从伦理的角度出发,但在澳大利亚执业时,在一个可接受的医学法律框架内。作者总结道:“既然OAIC已经澄清,可以从患者那里收集亲属的联系方式,并在不违反《隐私法》的情况下,用于通知他们他们的遗传风险,那么制定一项临床指南来帮助临床医生将是及时的。”每个州和地区的隐私监管机构对当地法律解释的考虑和指导将有助于这一点”。MJA继续在出版直接影响卫生政策和临床实践的指导方针和研究方面走在前列。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Important updates for clinical practice and health policy

This issue of the MJA features several articles that provide new guidelines and insights into the management and consequences of important clinical conditions.

Updated guidelines on the management of gestational diabetes are now published.1 The 2025 consensus recommendations from the Australasian Diabetes in Pregnancy Society (ADIPS) update the guidance for the screening, diagnosis and classification of hyperglycaemia in pregnancy based on available evidence and stakeholder consultation.2 These consensus recommendations, from Sweeting and colleagues, are important; the last time these guidelines were updated was in 2014.1 These updated recommendations raise the diagnostic glucose thresholds for gestational diabetes mellitus and clarify approaches to early pregnancy screening for women with risk factors for hyperglycaemia in pregnancy. An HbA1C measurement is now recommended with first trimester antenatal blood tests to assist practitioners with risk stratification. There is also guidance on considerations that need to be made for early oral glucose tolerance testing in high risk women. As rates of gestational diabetes continue to rise, diagnosis and management of this condition are likely to be within the scope of practice for most generalist medical practitioners, especially in regional and remote areas with poor access to specialist teams. These recommendations are a welcome update for medical practitioners.

Diabetes features in an article by Zhang and colleagues, which examined information from Diabetic Foot Services and linked it to Queensland Hospital Admitted Patient Data to assess the incidence, risk factors and length of stay for hospitalisations, with and without amputations, of people with diabetes-related foot ulcers (DFU).3 This is again an increasingly common condition in the population as rates of diabetes and its related complications increase. The incidence of DFU-related hospitalisations among people with DFU was high, although most did not involve amputations. The risk of DFU-related hospitalisation was higher for people with deep ulcers or severe peripheral artery disease. The authors argue that these findings could assist services determine which people with DFU would benefit most from intensive interventions, potentially averting large numbers of diabetes-related hospitalisations.

In another clinically focused article in this issue, Seeley and colleagues analysed data from the Australian postural orthostatic tachycardia syndrome (POTS) Patient Registry to assess the symptom burden, quality of life, and diagnosis history of people with POTS in South Australia.4 This is the first Australian study based on data from a registry of people with physician-confirmed POTS. The key findings were long delays between symptom onset and diagnosis despite seeing several physicians, reduced social engagement, high unemployment, and low quality of life for the relatively young people with POTS. The mean diagnostic delay in this study was longer than reported overseas, suggesting unique barriers in Australian health care. This will become more relevant in the future as infection with SARS-CoV-2 was the most common reported trigger for development of the condition.

An article with important advice for physicians who support patients with genetic diseases is a summary of the recently updated guidance from the Office of the Australian Information Commissioner (OAIC) clarifying clinicians’ discretion to assist patients with notifying their relatives about genetic risk without breaching federal privacy laws.5, 6 Tiller and Otlowski examine the clinician's role in this scenario.5 The authors discussed the challenge from the point of view of the patient, of their relatives and the clinician's role in managing expectations both from an ethical perspective but within an acceptable medico-legal framework while practising in Australia. The authors conclude that “Now that the OAIC has clarified that relatives’ contact details can be collected from patients and used to notify them about their genetic risk, without breaching the Privacy Act, the development of a clinical guideline to assist clinicians would be timely. Consideration and guidance from privacy regulators in each state and territory about the interpretation of local laws would assist with this”.

The MJA continues to be at the forefront of publishing guidelines and research that directly affect health policy and clinical practice.

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来源期刊
Medical Journal of Australia
Medical Journal of Australia 医学-医学:内科
CiteScore
9.40
自引率
5.30%
发文量
410
审稿时长
3-8 weeks
期刊介绍: The Medical Journal of Australia (MJA) stands as Australia's foremost general medical journal, leading the dissemination of high-quality research and commentary to shape health policy and influence medical practices within the country. Under the leadership of Professor Virginia Barbour, the expert editorial team at MJA is dedicated to providing authors with a constructive and collaborative peer-review and publication process. Established in 1914, the MJA has evolved into a modern journal that upholds its founding values, maintaining a commitment to supporting the medical profession by delivering high-quality and pertinent information essential to medical practice.
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