Jingya Zhang, Yongbo Lu, Ning Zhang, Wei Ning, Bin Zhu, Ying Mao
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Low quality sleep significantly increased the risk of incidence (OR:1.09, 95%CI:1.05-1.13), adverse progression (OR:1.55,95%CI:1.51-1.59), and specific mortality (OR:1.54, 95%CI:1.50-1.58) of breast cancer. Sleep duration >9 h had a poor effect on breast cancer-specific mortality (OR:1.45,95%CI:1.02-2.04).</p><p><strong>Conclusions: </strong>The available evidence points to sleep traits as primarily influencing progression in breast cancer patients and having a relatively small effect on breast cancer incidence. Prolonged sleep may lead to breast cancer-specific mortality, but more research is needed in the future to continue to explore the impact of sleep duration and breast cancer risk.</p>","PeriodicalId":14322,"journal":{"name":"International Journal of Public Health","volume":"70 ","pages":"1608535"},"PeriodicalIF":2.4000,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303857/pdf/","citationCount":"0","resultStr":"{\"title\":\"Sleep Traits to the Risk of Breast Cancer Disease Incidence, Adverse Progression and Mortality: Evidence From a Global Systematic Review and Meta-Analysis.\",\"authors\":\"Jingya Zhang, Yongbo Lu, Ning Zhang, Wei Ning, Bin Zhu, Ying Mao\",\"doi\":\"10.3389/ijph.2025.1608535\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>This study aimed to identify the effect of sleep traits on the risk of breast cancer incidence and adverse progression and mortality.</p><p><strong>Methods: </strong>Cohort studies measuring the relationship between sleep traits (including sleep quality and sleep duration) and breast cancer risk were eligible for inclusion. 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引用次数: 0
摘要
目的：本研究旨在确定睡眠特征对乳腺癌发病率、不良进展和死亡率的影响。方法：测量睡眠特征（包括睡眠质量和睡眠时间）与乳腺癌风险之间关系的队列研究符合纳入条件。我们检索了Web of Science、PubMed、EMBASE和Cochrane图书馆数据库，查找2014年至2024年间发表的研究。最大协变量校正比值比（OR）合并。根据异质性采用固定或随机效应模型。结果：34项研究符合纳入和排除标准。低质量睡眠显著增加乳腺癌发病率（OR:1.09, 95%CI:1.05-1.13）、不良进展（OR:1.55,95%CI:1.51-1.59）和特定死亡率（OR:1.54, 95%CI:1.50-1.58）的风险。睡眠时间90小时对乳腺癌特异性死亡率影响不大（OR:1.45,95%CI:1.02-2.04）。结论：现有证据表明，睡眠特征是影响乳腺癌患者病情发展的主要因素，对乳腺癌发病率的影响相对较小。长时间睡眠可能会导致乳腺癌特异性死亡率，但未来需要更多的研究来继续探索睡眠时间和乳腺癌风险的影响。
Sleep Traits to the Risk of Breast Cancer Disease Incidence, Adverse Progression and Mortality: Evidence From a Global Systematic Review and Meta-Analysis.
Objectives: This study aimed to identify the effect of sleep traits on the risk of breast cancer incidence and adverse progression and mortality.
Methods: Cohort studies measuring the relationship between sleep traits (including sleep quality and sleep duration) and breast cancer risk were eligible for inclusion. We searched the Web of Science, PubMed, EMBASE and Cochrane library databases for studies published between 2014 and 2024. Maximum covariate-adjusted odds ratio (OR) was combined. A fixed or a randomized effect model was applied according to the heterogeneity.
Results: 34 studies met the inclusion and exclusion criteria. Low quality sleep significantly increased the risk of incidence (OR:1.09, 95%CI:1.05-1.13), adverse progression (OR:1.55,95%CI:1.51-1.59), and specific mortality (OR:1.54, 95%CI:1.50-1.58) of breast cancer. Sleep duration >9 h had a poor effect on breast cancer-specific mortality (OR:1.45,95%CI:1.02-2.04).
Conclusions: The available evidence points to sleep traits as primarily influencing progression in breast cancer patients and having a relatively small effect on breast cancer incidence. Prolonged sleep may lead to breast cancer-specific mortality, but more research is needed in the future to continue to explore the impact of sleep duration and breast cancer risk.
期刊介绍：
The International Journal of Public Health publishes scientific articles relevant to global public health, from different countries and cultures, and assembles them into issues that raise awareness and understanding of public health problems and solutions. The Journal welcomes submissions of original research, critical and relevant reviews, methodological papers and manuscripts that emphasize theoretical content. IJPH sometimes publishes commentaries and opinions. Special issues highlight key areas of current research. The Editorial Board''s mission is to provide a thoughtful forum for contemporary issues and challenges in global public health research and practice.
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