prePSMA的临床试验方案：一项多中心、随机、非效性试验，术前前列腺特异性膜抗原正电子发射断层扫描/计算机断层扫描作为机器人辅助腹腔镜根治性前列腺切除术患者扩展盆腔淋巴结清扫的分诊方法。

IF 5.6 2区医学 Q1 UROLOGY & NEPHROLOGY

European urology focus Pub Date : 2025-07-28 DOI:10.1016/j.euf.2025.07.010

Lars F Qvigstad, Kirsti Aas, Andreas Tulipan, Knut H Hole, Anne H Storås, Clara Hammarström, Reza Ghiasvand, Stein H Holmedal, Viktor Berge

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引用次数: 0

摘要

prePSMA是一项随机对照试验，在该试验中，高风险前列腺癌患者和选定的中等风险疾病患者被随机分配到对照组，其中所有患者都接受扩展盆腔淋巴结清扫（ePLND），或实验组，仅对术前前列腺特异性膜抗原正电子发射断层扫描/计算机断层扫描结果阳性的患者进行ePLND。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Clinical Trial Protocol for prePSMA: A Multicenter, Randomized, Noninferiority Trial of Preoperative Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography as Triage for Extended Pelvic Lymph Node Dissection in Patients Scheduled for Robot-assisted Laparoscopic Radical Prostatectomy.

prePSMA is a randomized controlled trial in which patients with high-risk prostate cancer and selected cases with intermediate-risk disease are randomized to a control arm in which all patients undergo extended pelvic lymph node dissection (ePLND), or an experimental arm in which ePLND is only performed in patients with positive preoperative findings on prostate-specific membrane antigen positron emission tomography/computed tomography.

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来源期刊

European urology focus Medicine-Urology

CiteScore

10.40

自引率

3.70%

发文量

274

审稿时长

23 days

期刊介绍： European Urology Focus is a new sister journal to European Urology and an official publication of the European Association of Urology (EAU). EU Focus will publish original articles, opinion piece editorials and topical reviews on a wide range of urological issues such as oncology, functional urology, reconstructive urology, laparoscopy, robotic surgery, endourology, female urology, andrology, paediatric urology and sexual medicine. The editorial team welcome basic and translational research articles in the field of urological diseases. Authors may be solicited by the Editor directly. All submitted manuscripts will be peer-reviewed by a panel of experts before being considered for publication.