生物安全和免疫记忆对减少牲畜中比例依赖的炭疽传播的影响。

IF 1.5
Piu Samui, Sima Mandal, Jayanta Mondal
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引用次数: 0

摘要

通过改进的确定性SIRBV模型,结合非线性比例依赖的疾病传播率,描述了生物安全畜牧场中高致命性炭疽疾病的动态和炭疽疫苗接种的影响。计算了系统的基本再生数R0,并利用R0探讨了系统在稳态周围的存在性和渐近稳定性。当R0 = 1时,系统在无病稳态发生跨临界分岔。恢复源性免疫和疫苗源性免疫的减弱引发反向分叉,导致牲畜中炭疽热的重新出现。分数阶系统的动力学行为表明,增加免疫记忆有利于缩短系统对炭疽传播的根除时间。数值模拟表明,适当的疫苗接种和全面的生物安全协议将有助于防止炭疽传播和控制疾病引起的牛死亡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of biosecurity and immunological memory in curtailing ratio-dependent transmission of anthrax in livestock.

Delineating the dynamics of highly lethal anthrax disease in a biosecured livestock farm and impact of anthrax vaccination is presented through a modified deterministic $SIRBV$ model incorporating nonlinear ratio-dependent disease transmission rate. The basic reproduction number $(R_{0})$ of the system is computed and employed to explore the existence and asymptotic stability around the steady states of the system. The system experiences transcritical bifurcation at the disease-free steady state for $R_{0} = 1$. Waning of recovery-derived immunity and vaccination-derived immunity trigger backward bifurcation causing reemergence of anthrax in livestock. The dynamical behaviors of the fractional order system express that increased immunological memory will benefit to cut down the eradication time of anthrax transmission from the system. Numerical simulations suggest that appropriate vaccination and comprehensive biosecurity protocols would help to prevent the anthrax transmission and control the disease-induced deaths of cattle.

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