Irine Aleyamma Thomas, Angel Cham Philip, Neenu Anna Joseph, Ramiya Ramachandran Kaipuzha, Davis Thomas Pulimoottil
{"title":"急性腺样体炎继发的小儿炎症性Grisel综合征:一例罕见病例报告及文献复习。","authors":"Irine Aleyamma Thomas, Angel Cham Philip, Neenu Anna Joseph, Ramiya Ramachandran Kaipuzha, Davis Thomas Pulimoottil","doi":"10.1007/s12070-025-05568-4","DOIUrl":null,"url":null,"abstract":"<p><p>Grisel's syndrome is a rare condition characterized by non-traumatic atlantoaxial subluxation, typically secondary to inflammatory processes or surgical interventions in the head and neck region. The literature suggests a rare incidence of approximately 1:100,000,000 per year without gender predilection.The syndrome is often associated with an abnormal head posture and can lead to serious neurological complications if not diagnosed and treated promptly. This paper reviews the pathophysiology, clinical presentation, diagnostic approach, and management strategies for Grisel's syndrome, emphasizing the importance of early recognition to prevent morbidity. A 7-year-old boy presented with torticollis, head tilt to the left, nasal obstruction, purulent nasal discharge, headache, and fever for 3 days. Examination showed painful head tilt to left, with neck rotation to the right and no neurological deficits. Nasopharyngoscopy revealed inflamed adenoid tissue with purulent discharge. CT scan showed a Fielding type I rotatory atlantoaxial subluxation. He was treated with intravenous antibiotics, analgesics, and a cervical collar. He became symptomatically better after 7 days of treatment and on follow-up, he had fully recovered and returned to normal activities. We performed a systematic review of the literature following the preferred reporting items for Systematic reviews. Literature searches were conducted in web-based search engines using MeSH terms and key words. Grisel's syndrome, though rare, should be considered in pediatric patients presenting with painful torticollis following upper respiratory infections or head and neck procedures. Prompt diagnosis through radiographic imaging and early intervention can prevent severe complications and improve patient outcomes.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3267-3272"},"PeriodicalIF":0.4000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297179/pdf/","citationCount":"0","resultStr":"{\"title\":\"Inflammatory Pediatric Grisel Syndrome Secondary to Acute Adenoiditis: A Rare Case Report and Review of Literature.\",\"authors\":\"Irine Aleyamma Thomas, Angel Cham Philip, Neenu Anna Joseph, Ramiya Ramachandran Kaipuzha, Davis Thomas Pulimoottil\",\"doi\":\"10.1007/s12070-025-05568-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Grisel's syndrome is a rare condition characterized by non-traumatic atlantoaxial subluxation, typically secondary to inflammatory processes or surgical interventions in the head and neck region. The literature suggests a rare incidence of approximately 1:100,000,000 per year without gender predilection.The syndrome is often associated with an abnormal head posture and can lead to serious neurological complications if not diagnosed and treated promptly. This paper reviews the pathophysiology, clinical presentation, diagnostic approach, and management strategies for Grisel's syndrome, emphasizing the importance of early recognition to prevent morbidity. A 7-year-old boy presented with torticollis, head tilt to the left, nasal obstruction, purulent nasal discharge, headache, and fever for 3 days. Examination showed painful head tilt to left, with neck rotation to the right and no neurological deficits. Nasopharyngoscopy revealed inflamed adenoid tissue with purulent discharge. CT scan showed a Fielding type I rotatory atlantoaxial subluxation. He was treated with intravenous antibiotics, analgesics, and a cervical collar. He became symptomatically better after 7 days of treatment and on follow-up, he had fully recovered and returned to normal activities. We performed a systematic review of the literature following the preferred reporting items for Systematic reviews. Literature searches were conducted in web-based search engines using MeSH terms and key words. Grisel's syndrome, though rare, should be considered in pediatric patients presenting with painful torticollis following upper respiratory infections or head and neck procedures. 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Inflammatory Pediatric Grisel Syndrome Secondary to Acute Adenoiditis: A Rare Case Report and Review of Literature.
Grisel's syndrome is a rare condition characterized by non-traumatic atlantoaxial subluxation, typically secondary to inflammatory processes or surgical interventions in the head and neck region. The literature suggests a rare incidence of approximately 1:100,000,000 per year without gender predilection.The syndrome is often associated with an abnormal head posture and can lead to serious neurological complications if not diagnosed and treated promptly. This paper reviews the pathophysiology, clinical presentation, diagnostic approach, and management strategies for Grisel's syndrome, emphasizing the importance of early recognition to prevent morbidity. A 7-year-old boy presented with torticollis, head tilt to the left, nasal obstruction, purulent nasal discharge, headache, and fever for 3 days. Examination showed painful head tilt to left, with neck rotation to the right and no neurological deficits. Nasopharyngoscopy revealed inflamed adenoid tissue with purulent discharge. CT scan showed a Fielding type I rotatory atlantoaxial subluxation. He was treated with intravenous antibiotics, analgesics, and a cervical collar. He became symptomatically better after 7 days of treatment and on follow-up, he had fully recovered and returned to normal activities. We performed a systematic review of the literature following the preferred reporting items for Systematic reviews. Literature searches were conducted in web-based search engines using MeSH terms and key words. Grisel's syndrome, though rare, should be considered in pediatric patients presenting with painful torticollis following upper respiratory infections or head and neck procedures. Prompt diagnosis through radiographic imaging and early intervention can prevent severe complications and improve patient outcomes.
期刊介绍:
Indian Journal of Otolaryngology and Head & Neck Surgery was founded as Indian Journal of Otolaryngology in 1949 as a scientific Journal published by the Association of Otolaryngologists of India and was later rechristened as IJOHNS to incorporate the changes and progress.
IJOHNS, undoubtedly one of the oldest Journals in India, is the official publication of the Association of Otolaryngologists of India and is about to publish it is 67th Volume in 2015. The Journal published quarterly accepts articles in general Oto-Rhino-Laryngology and various subspecialities such as Otology, Rhinology, Laryngology and Phonosurgery, Neurotology, Head and Neck Surgery etc.
The Journal acts as a window to showcase and project the clinical and research work done by Otolaryngologists community in India and around the world. It is a continued source of useful clinical information with peer review by eminent Otolaryngologists of repute in their respective fields. The Journal accepts articles pertaining to clinical reports, Clinical studies, Research articles in basic and applied Otolaryngology, short Communications, Clinical records reporting unusual presentations or lesions and new surgical techniques. The journal acts as a catalyst and mirrors the Indian Otolaryngologist’s active interests and pursuits. The Journal also invites articles from senior and experienced authors on interesting topics in Otolaryngology and allied sciences from all over the world.
The print version is distributed free to about 4000 members of Association of Otolaryngologists of India and the e-Journal shortly going to make its appearance on the Springer Board can be accessed by all the members.
Association of Otolaryngologists of India and M/s Springer India group have come together to co-publish IJOHNS from January 2007 and this bondage is going to provide an impetus to the Journal in terms of international presence and global exposure.